Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephanie N. Schauer"'
Autor:
Thu H.M. Nguyen, Patricia E. Carreira, Francisco J. Sanchez-Luque, Stephanie N. Schauer, Allister C. Fagg, Sandra R. Richardson, Claire M. Davies, J. Samuel Jesuadian, Marie-Jeanne H.C. Kempen, Robin-Lee Troskie, Cini James, Elizabeth A. Beaven, Tristan P. Wallis, Jermaine I.G. Coward, Naven P. Chetty, Alexander J. Crandon, Deon J. Venter, Jane E. Armes, Lewis C. Perrin, John D. Hooper, Adam D. Ewing, Kyle R. Upton, Geoffrey J. Faulkner
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3730-3740 (2018)
Summary: LINE-1 (L1) retrotransposons are a source of insertional mutagenesis in tumor cells. However, the clinical significance of L1 mobilization during tumorigenesis remains unclear. Here, we applied retrotransposon capture sequencing (RC-seq) to
Externí odkaz:
https://doaj.org/article/02b2c6ba831b4bec8988f6149861dbe1
Autor:
Victor Billon, Francisco J. Sanchez-Luque, Jay Rasmussen, Gabriela O. Bodea, Daniel J. Gerhardt, Patricia Gerdes, Seth W. Cheetham, Stephanie N. Schauer, Prabha Ajjikuttira, Thomas J. Meyer, Cora E. Layman, Kimberly A. Nevonen, Natasha Jansz, Jose L. Garcia-Perez, Sandra R. Richardson, Adam D. Ewing, Lucia Carbone, Geoffrey J. Faulkner
Publikováno v:
Genome research. 32(7)
The retrotransposon LINE-1 (L1) is central to the recent evolutionary history of the human genome and continues to drive genetic diversity and germline pathogenesis. However, the spatiotemporal extent and biological significance of somatic L1 activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24afdca3efc56982e70ca770b29ed45a
https://pubmed.ncbi.nlm.nih.gov/35728967
https://pubmed.ncbi.nlm.nih.gov/35728967
Autor:
Geoffrey J. Faulkner, Patricia E. Carreira, John D. Hooper, Claire M. Davies, A.J. Crandon, Naven Chetty, Jane E. Armes, Jermaine Coward, Deon J. Venter, Francisco J. Sanchez-Luque, Robin-Lee Troskie, Stephanie N. Schauer, Sandra R. Richardson, Elizabeth A Beaven, Tristan Wallis, Marie-Jeanne H.C. Kempen, Kyle R. Upton, Thu H.M. Nguyen, Allister C. Fagg, J. Samuel Jesuadian, Adam D. Ewing, Lewis Perrin, Cini R. James
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3730-3740 (2018)
Summary: LINE-1 (L1) retrotransposons are a source of insertional mutagenesis in tumor cells. However, the clinical significance of L1 mobilization during tumorigenesis remains unclear. Here, we applied retrotransposon capture sequencing (RC-seq) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b964783c47c99b1b23b53fe480121670
http://www.sciencedirect.com/science/article/pii/S2211124718308714
http://www.sciencedirect.com/science/article/pii/S2211124718308714
Autor:
Didier Samuel, Stephanie N. Schauer, Daniel J. Gerhardt, Delphine Rapoud, Paola Nicoli, Michaela Kindlova, Sandra R. Richardson, Ruchi Shukla, Francisco J. Sanchez-Luque, Jamila Faivre, Alexandre Dos Santos, Serena Ghisletti, Patricia E. Carreira, Patricia Gerdes, Adam D. Ewing, Geoffrey J. Faulkner
Publikováno v:
Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (5), pp.639-653. ⟨10.1101/gr.226993.117⟩
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (5), pp.639-653. ⟨10.1101/gr.226993.117⟩
The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human malignancie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95e6561d04d7ec1fa51aeb51723d80b
https://hdl.handle.net/10668/12334
https://hdl.handle.net/10668/12334
Autor:
Paul Brennan, Allister C. Fagg, Daniel J. Gerhardt, Stephanie N. Schauer, Kyle R. Upton, Geoffrey J. Faulkner, Patricia E. Carreira, Sandra R. Richardson, Jun Wang, Adam D. Ewing, Michaela Kindlova, Santiago Morell, Bo Li, Patricia Gerdes, Guibo Li
Publikováno v:
Carreira, P E, Ewing, A D, Li, G, Schauer, S N, Upton, K R, Fagg, A C, Morell, S, Kindlova, M, Gerdes, P, Richardson, S R, Li, B, Gerhardt, D J, Wang, J, Brennan, P M & Faulkner, G J 2016, ' Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme ', Mobile D N A, vol. 7, 21 . https://doi.org/10.1186/s13100-016-0076-6
Mobile DNA
Carreira, P, Ewing, A D, Li, G, Schauer, S N, Upton, K R, Fagg, A C, Morell, S, Kindlova, M, Gerdes, P, Richardson, S R, Li, B, Gerhardt, D J, Jun, W, Brennan, P & Faulkner, G J 2016, ' Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme ', Mobile DNA . https://doi.org/10.1186/s13100-016-0076-6
Mobile DNA
Carreira, P, Ewing, A D, Li, G, Schauer, S N, Upton, K R, Fagg, A C, Morell, S, Kindlova, M, Gerdes, P, Richardson, S R, Li, B, Gerhardt, D J, Jun, W, Brennan, P & Faulkner, G J 2016, ' Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme ', Mobile DNA . https://doi.org/10.1186/s13100-016-0076-6
Background LINE-1 (L1) retrotransposons are a notable endogenous source of mutagenesis in mammals. Notably, cancer cells can support unusual L1 retrotransposition and L1-associated sequence rearrangement mechanisms following DNA damage. Recent report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8bc7cae257c727501f9cc064295b1e
https://zenodo.org/record/166405
https://zenodo.org/record/166405