Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephanie N. Oldham"'
Autor:
Jennifer L. Kaplan, Melissa A. Marshall, Chantel C. McSkimming, Daniel B. Harmon, James C. Garmey, Stephanie N. Oldham, Peter Hallowell, Coleen A. McNamara
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 779-794 (2015)
Objective: Macrophages are important producers of obesity-induced MCP-1; however, initial obesity-induced increases in MCP-1 production precede M1 macrophage accumulation in visceral adipose tissue (VAT). The initial cellular source of obesity-induce
Externí odkaz:
https://doaj.org/article/da87b27aafea4da5a93e33162a5af5d3
Autor:
James C. Garmey, Jennifer L Kaplan, Peter T. Hallowell, Melissa A. Marshall, Chantel McSkimming, Stephanie N. Oldham, Coleen A. McNamara, Daniel B. Harmon
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 779-794 (2015)
Molecular Metabolism
Molecular Metabolism
Objective Macrophages are important producers of obesity-induced MCP-1; however, initial obesity-induced increases in MCP-1 production precede M1 macrophage accumulation in visceral adipose tissue (VAT). The initial cellular source of obesity-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432a365894c0bf73d2c254b252c77772
https://doi.org/10.1016/j.molmet.2015.07.010
https://doi.org/10.1016/j.molmet.2015.07.010
Autor:
Harini Bagavant, Amanda C. Doran, Seshagiri Rao Nandula, Yogesh Scindia, Coleen A. McNamara, Dominika Nackiewicz, Umesh S. Deshmukh, Stephanie N. Oldham, Alexis Cutchins
Publikováno v:
The American Journal of Pathology. 179:651-660
The clinical association between hyperlipidemia and renal disease is well established, yet hyperlipidemia as a cause for renal disease is rare. Apolipoprotein E–deficient ( ApoE −/− ) mice develop hyperlipidemia and are a model for atherosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4f893b8ab6b65914926ccfb9360c011
https://doi.org/10.1016/j.ajpath.2011.04.029
https://doi.org/10.1016/j.ajpath.2011.04.029
Autor:
Nahum Meller, Hamid Deliri, Jordan Brewster, Hong Pei, Marcus D. Skaflen, Amanda C. Doran, Stephanie N. Oldham, James C. Garmey, Coleen A. McNamara, Ajay Kadakkal, Rohit Malhotra
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective— To determine whether increased 12/15-lipoxygenase (12/15LO) expression in vivo enhances neointimal formation in response to injury. Methods and Results— 12/15LO expression in the vessel wall is increased in animal models of metabolic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6deb0ff5a5d018038b62a2094501fc23
https://doi.org/10.1161/atvbaha.110.212068
https://doi.org/10.1161/atvbaha.110.212068
Autor:
R. Parker Slayton, Allison B. Lehtinen, Marcus D. Skaflen, Nahum Meller, Coleen A. McNamara, Amanda C. Doran, Stephen S. Rich, Stephanie N. Oldham, Michael J. Lipinski, Joseph Yeboah, Donald W. Bowden
Publikováno v:
Circulation Research. 106:1303-1311
Rationale : The gene encoding the helix–loop–helix transcription factor Id3 (inhibitor of differentiation-3) is located within atherosclerosis susceptibility loci of both mice and humans, yet its influence on atherosclerosis is not known. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5eff6ef763566f9ecc71ad77912021
https://doi.org/10.1161/circresaha.109.210294
https://doi.org/10.1161/circresaha.109.210294
Autor:
Coleen A. McNamara, Nahum Meller, R. Parker Slayton, Jae Bum Kim, Hamid Deliri, Stephanie N. Oldham, Amanda C. Doran, Alexis Cutchins, Susanna R. Keller
Publikováno v:
Circulation Research. 103:624-634
Adiponectin is an adipocyte-derived cytokine with beneficial effects on insulin sensitivity and the development of atherosclerosis. Id3 is a helix–loop–helix factor that binds to E-proteins such as E47 and inhibits their binding to DNA. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1089f23086c86dbf552c5bfe0c8ba3c
https://doi.org/10.1161/circresaha.108.175893
https://doi.org/10.1161/circresaha.108.175893
Autor:
Sotirios Tsimikas, Prasad Srikakulapu, Ayelet Gonen, Bruce Schirmer, Thomas A. Prohaska, Angela M. Taylor, Peter Hallowell, Joseph L. Witztum, Jennifer L. Kirby, Coleen A. McNamara, Heather M. Perry, Daniel B. Harmon, Jennifer L. Kaplan, Chantel McSkimming, Stephanie N. Oldham, James C. Garmey
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 36(4)
Objective— Little is known about the role(s) B cells play in obesity-induced metabolic dysfunction. This study used a mouse with B-cell–specific deletion of Id3 (Id3 Bcell KO ) to identify B-cell functions involved in the metabolic consequences o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93f88d08572f66dcca88b9e2eee3b4a
https://pubmed.ncbi.nlm.nih.gov/26868208
https://pubmed.ncbi.nlm.nih.gov/26868208
Autor:
Daniel Harmon, Stephanie N Oldham, Chantel C McSkimming, Heather M Perry, Jennifer L Kirby, Jennifer L Kaplan, Peter Hallowell, Bruce Schirmer, Sotirios Tsimikas, Angela Taylor, Coleen McNamara
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Innate B-1 B cells can protect against inflammatory disease through production of natural IgM antibodies, but little is known regarding their role in obesity-induced metabolic dysfunction. In this study, we explore the role murine B-1 B cells play in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8eef5c5613eb4c74412eb5bad0b2e7a
https://doi.org/10.1161/atvb.34.suppl_1.205
https://doi.org/10.1161/atvb.34.suppl_1.205
Autor:
Stephanie N. Oldham, Shawn P. Fahl, Timothy P. Bender, Coleen A. McNamara, Daniel B. Harmon, Joseph L. Witztum, Xuchu Que, Heather M. Perry, Sotirios Tsimikas, Ayelet Gonen
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 33(12)
Objective— Natural immunity is emerging as an important mediator of protection from atherogenesis. Natural IgM antibodies that recognize oxidation-specific epitopes on low-density lipoprotein or phospholipids and the B-1a B cells that produce them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cf1b99b6d1b4eac2719849bb95d94d
https://pubmed.ncbi.nlm.nih.gov/24226956
https://pubmed.ncbi.nlm.nih.gov/24226956
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Background B1 B cells [[Unable to Display Character: –]] the major producers of anti-inflammatory natural T15-IgM antibodies that promote tissue homeostasis [[Unable to Display Character: –]] have been identified in adipose tissue, but their role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec3bc6af281dd021e491405bbf5d8bc
https://doi.org/10.1161/atvb.33.suppl_1.a80
https://doi.org/10.1161/atvb.33.suppl_1.a80