Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stephanie N. Liu"'
Autor:
Stephanie N. Liu, Priya Agarwal, Katja Heinig, Asim Datye, Carolina Sturm‐Pellanda, Andrea Crugnola, Marc Arca, Dale Miles
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 6, Pp 1085-1096 (2023)
Abstract Alectinib, approved as 150 mg capsules for the treatment of adults with advanced ALK‐positive non‐small cell lung cancer, is being assessed in children with ALK‐positive solid and central nervous system tumors. An ad hoc pediatric‐fr
Externí odkaz:
https://doaj.org/article/387720650616442789e21d41ef9614bd
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 1, Pp 40-47 (2020)
Multiple doses of tenofovir disoproxil fumarate (TDF) together with emtricitabine is effective for HIV preexposure prophylaxis (PrEP). TDF is converted to tenofovir (TFV) in circulation, which is subsequently cleared via tubular secretion by organic
Externí odkaz:
https://doaj.org/article/42017aa69bcb4f1e8e691c66b3c7ceec
Autor:
Dan Lu, Stephanie N. Liu, Michael Z. Liao, Dale Miles, Divya Samineni, Matts Kågedal, Chunze Li
Publikováno v:
Clinical Pharmacology and Therapeutics
Antibody-drug conjugates (ADCs) combine the specificity of an antibody with the cytotoxicity of a chemical agent. They represent a rapidly evolving area of oncology drug development and hold significant promise. There are currently nine ADCs on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b0919e0349386ef91ec22d0611b982
https://doi.org/10.1002/cpt.2278
https://doi.org/10.1002/cpt.2278
Autor:
Fjodor Melnikov, Chunze Li, Whitney P. Kirschbrown, Tong Lu, Jin Y. Jin, Eleonora Restuccia, Tanja Badovinac Crnjevic, Z. Machackova, Sandhya Girish, Stephanie N. Liu
Publikováno v:
Journal of Clinical Pharmacology
PERJETA (pertuzumab), administered with Herceptin (trastuzumab), is used in the treatment of human epidermal growth factor receptor 2‐positive breast cancer. Pertuzumab is currently approved with an initial loading dose of 840 mg, followed by a 420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c6c91f2d7951cfbaff947505566724
http://europepmc.org/articles/PMC8361934
http://europepmc.org/articles/PMC8361934
Autor:
Stephanie N. Liu, Chunze Li
Publikováno v:
Cancer Chemotherapy and Pharmacology
Antibody–drug conjugates (ADCs) are important molecular entities in the treatment of cancer. These conjugates combine the target specificity of monoclonal antibodies with the potent anti-cancer activity of small-molecule therapeutics. The complex s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedd8647b05115ad7d4948f0de7f515b
https://doi.org/10.1007/s00280-021-04250-0
https://doi.org/10.1007/s00280-021-04250-0
Autor:
Weize Huang, Junyi Li, Michael Z. Liao, Stephanie N. Liu, Jiajie Yu, Jing Jing, Naoki Kotani, Lynn Kamen, Sebastian Guelman, Dale R. Miles
Publikováno v:
Clinical pharmacology and therapeutics. 112(5)
Adoptive cell therapies (ACTs) have shown transformative efficacy in oncology with five US Food and Drug Administration (FDA) approvals for chimeric antigen receptor (CAR) T-cell therapies in hematological malignancies, and promising activity for T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a45cc75567664a749fdcd8fbea301a6
https://pubmed.ncbi.nlm.nih.gov/34888856
https://pubmed.ncbi.nlm.nih.gov/34888856
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 1, Pp 40-47 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 1, Pp 40-47 (2020)
Multiple doses of tenofovir disoproxil fumarate (TDF) together with emtricitabine is effective for HIV preexposure prophylaxis (PrEP). TDF is converted to tenofovir (TFV) in circulation, which is subsequently cleared via tubular secretion by organic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85234f7d285c3827a42623095c997de
https://doi.org/10.1002/psp4.12481
https://doi.org/10.1002/psp4.12481
Autor:
Zeruesenay Desta, Philip Lazarus, Christy J. W. Watson, Jessica Bo Li Lu, Stephanie N. Liu, Brandon T. Gufford
Publikováno v:
Drug Metab Dispos
Integrase strand transfer inhibitor (INSTI)–based regimens dominate initial human immunodeficiency virus treatment. Most INSTIs are metabolized predominantly via UDP-glucuronosyltransferases (UGTs). For drugs predominantly metabolized by UGTs, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bee077d19e3e91712b496f4a8524203
https://doi.org/10.1124/dmd.118.085035
https://doi.org/10.1124/dmd.118.085035
Letter to the editor: Model-based simulation to support the extended dosing regimens of atezolizumab
Autor:
Nitzan Sternheim, Marcus Ballinger, Julien Mazieres, Rene Bruno, Benjamin Wu, Stephanie N. Liu, Hina Patel
Publikováno v:
European journal of clinical pharmacology. 77(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e578d967f99ba17a94db0ffceec326f
https://pubmed.ncbi.nlm.nih.gov/33237384
https://pubmed.ncbi.nlm.nih.gov/33237384
Autor:
Richard F. Bergstrom, Stephanie N. Liu, Samir K. Gupta, Brandon T. Gufford, Peter L. Anderson, Lane R. Bushman, Jessica Bo Li Lu, Zeruesenay Desta
Publikováno v:
Clin Pharmacol Ther
In a randomized, cross-over study in healthy volunteers (N=14), 2 g probenecid (PRO)-boosted pharmacokinetics of single dose 600 mg tenofovir disoproxil fumarate (TDF) / 400 mg emtricitabine (FTC) (Treatment, T +PRO) was compared with the current On-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c05befe6621a6ccf184b398ac319c5
https://europepmc.org/articles/PMC7703849/
https://europepmc.org/articles/PMC7703849/
