Retinal Microvascular Dysfunction Occurs Early and Similarly in Mild Alzheimer’s Disease and Primary-Open Angle Glaucoma Patients

Autor: Stephanie Mroczkowska, Hala Shokr, Alexandra Benavente-Pérez, Anil Negi, Peter Bentham, Doina Gherghel

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 22; Pages: 6702
Mroczkowska, S, Shokr, H, Benavente-Pérez, A, Negi, A, Bentham, P & Gherghel, D 2022, ' Retinal Microvascular Dysfunction Occurs Early and Similarly in Mild Alzheimer’s Disease and Primary-Open Angle Glaucoma Patients ', Journal of Clinical Medicine, vol. 11, no. 22, 6702 . https://doi.org/10.3390/jcm11226702

Purpose: To assess the similarities and differences in retinal microvascular function between mild Alzheimer’s disease (AD) patients, early-stage primary open angle glaucoma (POAG) patients and healthy controls. Methods: Retinal vessel reactivity t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b71f1cab0cdb5848b88f755eb89416e
https://doi.org/10.3390/jcm11226702

Patients with early age-related macular degeneration exhibit signs of macro- and micro-vascular disease and abnormal blood glutathione levels

Autor: Doina Gherghel, Anikó Ekárt, Stephanie Mroczkowska, Lu Qin, Sunni R. Patel, Jonathan Gibson

Publikováno v: Graefe's Archive for Clinical and Experimental Ophthalmology. 252:23-30

Background: This pilot study aimed to investigate systemic and retinal vascular function and their relationship to circulatory markers of cardiovascular risk in early age-related macular degeneration (AMD) patients without any already diagnosed syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2769410ae3c12b2fdd8478ba1dc29bf9
https://doi.org/10.1007/s00417-013-2418-0

Systemic circulatory influences on retinal microvascular function in middle-age individuals with low to moderate cardiovascular risk

Autor: Anikó Ekárt, Sunni R. Patel, Stephanie Mroczkowska, Swathi Seshadri, Doina Gherghel, Lu Qin

Publikováno v: Acta ophthalmologica. 93(4)

Purpose: To investigate the relationship between retinal microvascular reactivity, circulatory markers for CVD risk and systemic antioxidative defence capacity in healthy middle-aged individuals with low to moderate risk of CVD. Methods: Retinal vasc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da2d7be32249491564e359fdbcbe9c4
https://pubmed.ncbi.nlm.nih.gov/25487686

Retinal vascular dysfunction relates to cognitive impairment in Alzheimer disease

Autor: Doina Gherghel, Lu Qin, Peter Bentham, Alexandra Benavente-Perez, Stephanie Mroczkowska, Sunni R. Patel

Publikováno v: Scopus-Elsevier

Cerebral vascular dysregulation has been increasingly implicated as a risk factor in the development of Alzheimer disease (AD)1; however, because of the difficulties associated with assessing and visualizing the cerebral vasculature directly, the abi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a602e61b18daad92aadc0a150803eb
https://pubmed.ncbi.nlm.nih.gov/23939264

Coexistence of macro- and micro-vascular abnormalities in newly diagnosed normal tension glaucoma patients

Autor: Doina Gherghel, Stephanie Mroczkowska, Velota Sung, Anil Negi, Lu Qin, Alexandra Benavente-Perez, Anikó Ekárt, Carole Atkins, Sunni R. Patel, Sarita Jacob

Publikováno v: Acta ophthalmologica. 90(7)

Purpose: To investigate the coexistence of ocular microvascular and systemic macrovascular abnormalities in early stage, newly diagnosed and previously untreated normal tension glaucoma patients (NTG). Methods: Retinal vascular reactivity to flickeri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa517b81439265675284e6c0f16089c9
https://pubmed.ncbi.nlm.nih.gov/22998650