Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephanie Merz"'
Autor:
Andreas Hähle, Thomas M Geiger, Stephanie Merz, Christian Meyners, Mao Tianqi, Jürgen Kolos, Felix Hausch
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221926 (2019)
The protein factor Glomulin (Glmn) is a regulator of the SCF (Skp1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. Mutations of Glmn lead to glomuvenous malformations. Glmn has been reported to be associated with FK506-binding proteins (FKBP
Externí odkaz:
https://doaj.org/article/eb801d8576204153a43254d72f82e7ae
Publikováno v:
Biomolecules, Vol 9, Iss 1, p 35 (2019)
The FK506-binding protein 51 (FKBP51) has emerged as a key regulator of endocrine stress responses in mammals and as a potential therapeutic target for stress-related disorders (depression, post-traumatic stress disorder), metabolic disorders (obesit
Externí odkaz:
https://doaj.org/article/4c671e79cc424bf6adb6c9651383f84e
Autor:
Martha C. Taubert, Jürgen M. Kolos, Christian Meyners, Thomas M. Geiger, Andreas Bracher, Patrick L. Purder, Tim Heymann, Pablo Wessig, Andreas M. Voll, Nils C. Gassen, Anna Charalampidou, Felix Hausch, Stephanie Merz, Thomas Bajaj
Publikováno v:
Angewandte Chemie. 133:13366-13372
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7ccf4922205c36b9eb05b01bf872ee
https://doi.org/10.1002/ange.202017352
https://doi.org/10.1002/ange.202017352
Autor:
Stephanie Merz, Felix Hausch, Andreas M. Voll, Patrick L. Purder, Wisely Oki Sugiarto, Michael Bauder, Tim Heymann, Christian Meyners
Publikováno v:
Journal of medicinal chemistry. 64(6)
The FK506-binding protein 51 (FKBP51) emerged as a key player in several diseases like stress-related disorders, chronic pain, and obesity. Linear analogues of FK506 called SAFit were shown to be highly selective for FKBP51 over its closest homologue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07383e4fa788acd0ddb9b755aae709d
https://pubmed.ncbi.nlm.nih.gov/33666419
https://pubmed.ncbi.nlm.nih.gov/33666419
Autor:
Stephanie Merz, Andrea Krumm, Olivier J. Switzeny, Wynand P. Roos, Carmen Loquai, Steve Quiros, Markus Christmann, Bernd Kaina
Publikováno v:
Oncotarget
In the treatment of metastatic melanoma, a highly therapy-refractory cancer, alkylating agents are used and, for the subgroup of BRAFV600E cancers, the B-Raf inhibitor vemurafenib. Although vemurafenib is initially beneficial, development of drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d377582154141c5e52c08d008b4891
http://europepmc.org/articles/PMC4350346
http://europepmc.org/articles/PMC4350346
Publikováno v:
Biomolecules, Vol 9, Iss 1, p 35 (2019)
Biomolecules
Biomolecules
The FK506-binding protein 51 (FKBP51) has emerged as a key regulator of endocrine stress responses in mammals and as a potential therapeutic target for stress-related disorders (depression, post-traumatic stress disorder), metabolic disorders (obesit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11729f5b3e50ce7ca7bc53db2a1abc2
https://doi.org/10.3390/biom9010035
https://doi.org/10.3390/biom9010035