Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephanie Makhoul"'
Autor:
Stephanie Makhoul, Katharina Trabold, Stepan Gambaryan, Stefan Tenzer, Daniele Pillitteri, Ulrich Walter, Kerstin Jurk
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-20 (2019)
Abstract Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα, part of the GPIb-IX-V complex, has several physiological ligands such as
Externí odkaz:
https://doaj.org/article/72902ec742954bcbb54c17bfd8893815
Autor:
Kerstin Jurk, Julia Sudnitsyna, Valentina Shpakova, Natalia Rukoyatkina, Michael Panteleev, Stepan Gambaryan, Stephanie Makhoul
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5405, p 5405 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5405, p 5405 (2021)
Curcumin is a natural bioactive component derived from the turmeric plant Curcuma longa, which exhibits a range of beneficial activities on human cells. Previously, an inhibitory effect of curcumin on platelets was demonstrated. However, it is unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47452bee894cd6673811d200c0fd3948
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
Volume 21
Issue 23
Distinct membrane receptors activate platelets by Src-family-kinase (SFK)-, immunoreceptor-tyrosine-based-activation-motif (ITAM)-dependent stimulation of spleen tyrosine kinase (Syk). Recently, we reported that platelet activation via glycoprotein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390eb023cb969e7d5913767ad7a23fd9
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 176 (2019)
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 176 (2019)
The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9489740614e463b54afdf37ac3a19234
Autor:
Jens Lutz, Kerstin Jurk, Mareike Döhrmann, Kathrin Gross, Beate E. Kehrel, Stephanie Makhoul, Daniele Pillitteri, Manuela Krause, Charis von Auer, Ivo Volf, Ulrich Walter
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(7)
Thrombin converts fibrinogen to fibrin and activates blood and vascular cells in thrombo-inflammatory diseases. Platelets are amplifiers of thrombin formation when activated by leukocyte- and vascular cell-derived thrombin. CD36 on platelets acts as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b52a30e372dd47e6400606df814137
https://pubmed.ncbi.nlm.nih.gov/32463151
https://pubmed.ncbi.nlm.nih.gov/32463151
Autor:
Kerstin Jurk, Katharina Trabold, Ulrich Walter, Stepan Gambaryan, Stephanie Makhoul, Stefan Tenzer, Daniele Pillitteri
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-20 (2019)
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-20 (2019)
Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα, part of the GPIb-IX-V complex, has several physiological ligands such as von Will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ab8664bd11e14abf835327ee79038c
http://europepmc.org/articles/PMC6743169
http://europepmc.org/articles/PMC6743169
Autor:
Marina Panova-Noeva, Philip Wenzel, Wolfram Ruf, Véronique Regnault, Stephanie Makhoul, Jeremy Lagrange
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, 2019, 8 (11), pp.1990. ⟨10.3390/jcm8111990⟩
Volume 8
Issue 11
Journal of Clinical Medicine, Vol 8, Iss 11, p 1990 (2019)
Journal of Clinical Medicine, 2019, 8 (11), pp.1990. ⟨10.3390/jcm8111990⟩
Volume 8
Issue 11
Journal of Clinical Medicine, Vol 8, Iss 11, p 1990 (2019)
International audience; Background: The direct oral anticoagulant rivaroxaban inhibiting specifically activated factor X (FXa) causes delayed thrombin generation (TG) as measured by calibrated automated thrombography (CAT). The implications of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d56462fa6b1f7ee513bba70f721a7c
https://hal.univ-lorraine.fr/hal-03565408
https://hal.univ-lorraine.fr/hal-03565408
Autor:
Stephanie Makhoul, Ulrich Walter, Elena Walter, René P. Zahedi, Kerstin Jurk, Albert Smolenski, Oliver Pagel, Stepan Gambaryan, Albert Sickmann
Publikováno v:
Nitric oxide : biology and chemistry. 76
Platelets are circulating sentinels of vascular integrity and are activated, inhibited, or modulated by multiple hormones, vasoactive substances or drugs. Endothelium- or drug-derived NO strongly inhibits platelet activation via activation of the sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c2dcdbe6baf75a1d444e58899d585b
https://pubmed.ncbi.nlm.nih.gov/29550521
https://pubmed.ncbi.nlm.nih.gov/29550521