Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephanie M. Yoder"'
Autor:
Karla E. Merz, Ragadeepthi Tunduguru, Miwon Ahn, Vishal A. Salunkhe, Rajakrishnan Veluthakal, Jinhee Hwang, Supriyo Bhattacharya, Erika M. McCown, Pablo A. Garcia, Chunxue Zhou, Eunjin Oh, Stephanie M. Yoder, Jeffrey S. Elmendorf, Debbie C. Thurmond
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Skeletal muscle accounts for ~80% of insulin-stimulated glucose uptake. The Group I p21–activated kinase 1 (PAK1) is required for the non-canonical insulin-stimulated GLUT4 vesicle translocation in skeletal muscle cells. We found that the abundance
Externí odkaz:
https://doaj.org/article/e88ac9a07c75452aa77f8a95a9d4da38
Autor:
Karla E. Merz, Ragadeepthi Tunduguru, Miwon Ahn, Vishal A. Salunkhe, Rajakrishnan Veluthakal, Jinhee Hwang, Supriyo Bhattacharya, Erika M. McCown, Pablo A. Garcia, Chunxue Zhou, Eunjin Oh, Stephanie M. Yoder, Jeffrey S. Elmendorf, Debbie C. Thurmond
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Skeletal muscle accounts for ~80% of insulin-stimulated glucose uptake. The Group I p21–activated kinase 1 (PAK1) is required for the non-canonical insulin-stimulated GLUT4 vesicle translocation in skeletal muscle cells. We found that the abundance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48991131eed0677bf074096c5fa2a04
https://pubmed.ncbi.nlm.nih.gov/35222279
https://pubmed.ncbi.nlm.nih.gov/35222279
Autor:
Zhanxiang Wang, Latha Ramalingam, Eunjin Oh, Debbie C. Thurmond, Ragadeepthi Tunduguru, Miwon Ahn, Stephanie M. Yoder
Publikováno v:
Diabetologia. 59:2145-2155
Human islets from type 2 diabetic donors are reportedly 80% deficient in the p21 (Cdc42/Rac)-activated kinase, PAK1. PAK1 is implicated in beta cell function and maintenance of beta cell mass. We questioned the mechanism(s) by which PAK1 deficiency p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4acf485fa3ff7da99c384156de70aa
https://doi.org/10.1007/s00125-016-4042-0
https://doi.org/10.1007/s00125-016-4042-0
Autor:
Erika M. Olson, Ragadeepthi Tunduguru, Karla E. Merz, Vishal A. Salunkhe, Stephanie M. Yoder, Miwon Ahn, Debbie C. Thurmond, Rajakrishnan Veluthakal, Jing Zhang, Eunjin Oh
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f1384e4dd65f71887089b17be085f98
https://doi.org/10.1096/fasebj.2020.34.s1.04704
https://doi.org/10.1096/fasebj.2020.34.s1.04704
Publikováno v:
Journal of Biological Chemistry. 289:11476-11487
Second-phase insulin secretion sustains insulin release in the face of hyperglycemia associated with insulin resistance, requiring the continued mobilization of insulin secretory granules to the plasma membrane. Cdc42, the small Rho family GTPase rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaffdbc0f0e218b6957a693cc265d819
https://doi.org/10.1074/jbc.m114.559328
https://doi.org/10.1074/jbc.m114.559328
Autor:
Lawrence A. Quilliam, Erica M. Kepner, Stephanie M. Yoder, Eunjin Oh, Debbie C. Thurmond, Zhanxiang Wang, Michael A. Kalwat
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 301:E1072-E1080
Second-phase insulin release requires the sustained mobilization of insulin granules from internal storage pools to the cell surface for fusion with the plasma membrane. However, the detailed mechanisms underlying this process remain largely unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b2d694b2c027e04771de895a5f860d
https://doi.org/10.1152/ajpendo.00312.2011
https://doi.org/10.1152/ajpendo.00312.2011
Publikováno v:
Physiology & Behavior. 105:82-88
The lymph fistula rat model has traditionally been used to study the intestinal absorption of nutrients, especially lipids, but recently this model has also been used for studying the secretion of incretin hormones by the small intestine. The small i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb92d2f003633e2affacabd0596650c
https://doi.org/10.1016/j.physbeh.2011.04.056
https://doi.org/10.1016/j.physbeh.2011.04.056
Autor:
Paulo J.F. Martins, Randy J. Seeley, Tammy L. Kindel, Ronald J. Jandacek, Stephanie M. Yoder, David A. D'Alessio, Silvana Obici, Patrick Tso
Publikováno v:
Obesity. 19:380-387
Roux-en-y gastric bypass (RYGB) surgery rapidly improves glucose tolerance and reverses insulin resistance in obese patients. It has been hypothesized that this effect is mediated by the diversion of nutrients from the proximal small intestine. We ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf50d8e7811d25cdbdc845f099ba51a3
https://doi.org/10.1038/oby.2010.263
https://doi.org/10.1038/oby.2010.263
Publikováno v:
Annals of the New York Academy of Sciences. 1207:E44-E51
The lymph fistula rat has been used for studying intestinal absorption of nutrients, especially lipids. Lipid absorption begins with the digestion of triacylglycerol (TAG) to form 2-monoacylglycerol (2-MAG) and fatty acids (FA), which are then incorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2756d4211f4b9e65a39742692c348aec
https://doi.org/10.1111/j.1749-6632.2010.05753.x
https://doi.org/10.1111/j.1749-6632.2010.05753.x
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G299-G305
After the ingestion of nutrients, secretion of the incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by the enteroendocrine cells increases rapidly. Previous studies have shown that oral ingestio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31425903732ce865a40b9271de567244
https://doi.org/10.1152/ajpgi.90601.2008
https://doi.org/10.1152/ajpgi.90601.2008