Výsledky vyhledávání - "Stephanie M. Stacey"

Disruption of an EAAT-Mediated Chloride Channel in a Drosophila Model of Ataxia

Autor: Donald J. van Meyel, Tiago Ferreira, Stephanie M. Stacey, Neda Parinejad, Emilie Peco

Patients with Type 6 episodic ataxia (EA6) have mutations of the excitatory amino acid transporter EAAT1 (also known as GLAST), but the underlying pathophysiological mechanism for EA6 is not known. EAAT1 is a glutamate transporter expressed by astroc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36f5d5263100bb8dd521b9f8af2f758
https://europepmc.org/articles/PMC6705562/

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Drosophila astrocytes cover specific territories of CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch

Autor: Darius Camp, Matthias Landgraf, Sejal Davla, Emilie Peco, Stephanie M. Stacey, Don J. Van Meyel

Publikováno v: Development.

Astrocytes are recognized as critical elements in the formation, fine-tuning, function and plasticity of neural circuits in the central nervous system. However, important questions remain unanswered about the mechanisms instructing astrocyte cell fat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f736e5448cc6384c959bd682081ac4f
https://doi.org/10.1242/dev.133165

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Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion

Autor: Stephanie M. Stacey, Donald J van Meyel, Graham B. Thomas, Nara I. Muraro, Emilie Peco, Richard A. Baines, Alain Labbé

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

In the mammalian CNS, glial cells expressing excitatory amino acid transporters (EAATs) tightly regulate extracellular glutamate levels to control neurotransmission and protect neurons from excitotoxic damage. Dysregulated EAAT expression is associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7809f9fa75da9e0c2ba3be70ab22ba75
https://pubmed.ncbi.nlm.nih.gov/20980602

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Longitudinal glia in the fly CNS: pushing the envelope on glial diversity and neuron-glial interactions

Autor: Donald J. van Meyel, Graham B. Thomas, Alain Labbé, Stephanie M. Stacey

Publikováno v: Neuron glia biology. 3(1)

Interactions between neurons and glial cells are crucial for nervous system development and function in all complex organisms, and many functional, morphological and molecular features of glia are well conserved among species. Here we review studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d785fb51ec0cb03cc4f1d2b1cab26df
https://pubmed.ncbi.nlm.nih.gov/18634575

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