Výsledky vyhledávání - "Stephanie M. Shelly"

Molecular imaging of lymphoid organs and immune activation using positron emission tomography with a new 18F-labeled 2′-deoxycytidine analog

Autor: Michael E. Phelps, Nagichettiar Satyamurthy, Owen N. Witte, Evan Nair-Gill, Chengyi J. Shu, Caius G. Radu, Jorge R. Barrio, Stephanie M. Shelly

Publikováno v: Nature medicine

Monitoring immune function with molecular imaging could have a considerable impact on the diagnosis and treatment evaluation of immunological disorders and therapeutic immune responses. Positron emission tomography (PET) is a molecular imaging modali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23e914d2c064e64e6257b57306ef821
http://europepmc.org/articles/PMC2720060

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Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain

Autor: Antoni Ribas, Caius G. Radu, Haumith Khan-Farooqi, Muh-Shi Lin, Stephanie M. Shelly, Linda M. Liau, Chengyi J. Shu, Meng Yin Yang, Horacio Soto, Owen N. Witte, Robert M. Prins, Dan D. Vo

Publikováno v: Cancer Immunology, Immunotherapy. 57:1279-1289

It is commonly believed that T cells have difficulty reaching tumors located in the brain due to the presumed "immune privilege" of the central nervous system (CNS). Therefore, we studied the biodistribution and anti-tumor activity of adoptively tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3b8e740a686445da86772db5df7dbb
https://doi.org/10.1007/s00262-008-0461-1

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Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen

Autor: Robert M. Prins, Stephanie M. Shelly, Michael E. Phelps, Antoni Ribas, Dan D. Vo, Owen N. Witte, Caius G. Radu, Chengyi J. Shu

Publikováno v: International immunology, vol 21, iss 2
International Immunology

Adoptive transfer (AT) T-cell therapy provides significant clinical benefits in patients with advanced melanoma. However, approaches to non-invasively visualize the persistence of transferred T cells are lacking. We examined whether positron emission

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32608b45cb1aa2a0ffdb93dbdd715b92
https://escholarship.org/uc/item/3d85w2m3

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Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis

Autor: Chengyi J. Shu, Michael E. Phelps, Caius G. Radu, Owen N. Witte, Stephanie M. Shelly

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 104(6)

2-[ 18 F]Fluoro-2-deoxy- d -glucose positron emission tomography ([ 18 F]FDG PET) detection of the up-regulated glycolysis associated with malignant transformation is a noninvasive imaging technique used extensively in cancer diagnosis. Although stri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222b64bf3046cbfca157281952c331a0
https://pubmed.ncbi.nlm.nih.gov/17261805

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Visualization of a primary anti-tumor immune response by positron emission tomography

Autor: Amar Nijagal, Pritha Ray, Caius G. Radu, Young Ji Kim, Stephanie M. Shelly, Owen N. Witte, Sanjiv S. Gambhir, Chengyi J. Shu, Shuling Guo

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 102(48)

Current methodologies that monitor immune responses rely on invasive techniques that sample tissues at a given point in time. New technologies are needed to elucidate the temporal patterns of immune responses and the spatial distribution of immune ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce324ac35d38ec02a9d131402995aa5
https://pubmed.ncbi.nlm.nih.gov/16293690

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