Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephanie M. Rathmann"'
Autor:
John F. Valliant, Anthony F. Rullo, Saman Sadeghi, Nancy Janzen, Afaf R. Genady, Stephanie M. Rathmann, Shannon Czorny, Varun C. Anipindi
Publikováno v:
Molecular Pharmaceutics. 18:2647-2656
Building on clinical case reports of the abscopal effect, there has been considerable interest in the synergistic effects of radiation and immunotherapies for the treatment of cancer. Here, the first radiolabeled antibody-recruiting small molecule th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b8cc96372347559fe5b5b3948ddfd6
https://doi.org/10.1021/acs.molpharmaceut.1c00187
https://doi.org/10.1021/acs.molpharmaceut.1c00187
Autor:
Nader El-Sayes, Natalie Mercanti, Alyssa Vito, Stephanie M. Rathmann, John F. Valliant, Karen L. Mossman
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4843, p 4843 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4843, p 4843 (2021)
Triple negative breast cancer (TNBC) is an aggressive subtype of the disease with poor clinical outcomes and limited therapeutic options. Immune checkpoint blockade (CP) has surged to the forefront of cancer therapies with widespread clinical success
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9250e8fa2e020271a36dc0f9f29336ef
https://pubmed.ncbi.nlm.nih.gov/34063642
https://pubmed.ncbi.nlm.nih.gov/34063642
Autor:
Lynn C. Francesconi, Nancy Janzen, Alyssa Vito, Stephanie M. Rathmann, John F. Valliant, Abdolreza Yazdani, Zainab Ahmad, Holly A. Bilton, Afaf R. Genady, Brian M. Zeglis, Shannon Czorny
Publikováno v:
Journal of Medicinal Chemistry. 59:9381-9389
A high yield synthesis of a novel, small molecule, bisphosphonate-modified trans-cyclooctene (TCO-BP, 2) that binds to regions of active bone metabolism and captures functionalized tetrazines in vivo, via the bioorthogonal inverse electron demand Die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69296f076cde874642c66d488809a35a
https://doi.org/10.1021/acs.jmedchem.6b00938
https://doi.org/10.1021/acs.jmedchem.6b00938
Publikováno v:
Canadian Journal of Chemistry. 94:773-780
Molecular probes that target specific markers expressed in solid tumours are in demand for cancer imaging and radionuclide therapy applications. The synthesis, characterization, and in vivo evaluation of radioiodinated triazoles designed as probes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1a159be6d0d2431dea33aafe4d9bc1
https://doi.org/10.1139/cjc-2016-0239
https://doi.org/10.1139/cjc-2016-0239
Autor:
Stephanie M. Rathmann, Zainab Ahmad, John F. Valliant, Holly A. Bilton, Denis P. Snider, Samantha R. Slikboer
Publikováno v:
Radiopharmaceutical Chemistry ISBN: 9783319989464
Technetium-99m (99mTc) is a radiometal that has nearly ideal nuclear properties for diagnostic nuclear medicine imaging, which has helped make it high impact and extensively utilized radionuclide in medicine. 99mTc-based imaging—which can be done u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b6f5218167412bf55550a5a124f67c6
https://doi.org/10.1007/978-3-319-98947-1_18
https://doi.org/10.1007/978-3-319-98947-1_18
Publikováno v:
Nuclear Medicine and Biology. :S12-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a31dade133b406fecb1268ae5785582b
https://doi.org/10.1016/s0969-8051(19)30223-9
https://doi.org/10.1016/s0969-8051(19)30223-9
Publikováno v:
Journal of Medical Imaging and Radiation Sciences. 50:S32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1a4d6ceff04a43652e5a025a4d91f6
https://doi.org/10.1016/j.jmir.2019.03.097
https://doi.org/10.1016/j.jmir.2019.03.097
Autor:
Omid Beiraghi, Megan Blacker, Zoya Naperstkow, John F. Valliant, Jeff Kent, Paul J. Berti, Nancy Janzen, Hussain Alarabi, Stephanie M. Rathmann, Shannon Czorny, Salma Al-Karmi, Lisset Llano, Afaf R. Genady, Alyssa Vito
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167425 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167425 (2016)
A convenient strategy to radiolabel a hydrazinonicotonic acid (HYNIC)-derived tetrazine with 99mTc was developed, and its utility for creating probes to image bone metabolism and bacterial infection using both active and pretargeting strategies was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7653d5db1628d69411bf0c417440e9
http://europepmc.org/articles/PMC5147877
http://europepmc.org/articles/PMC5147877
Autor:
Abdolreza, Yazdani, Holly, Bilton, Alyssa, Vito, Afaf R, Genady, Stephanie M, Rathmann, Zainab, Ahmad, Nancy, Janzen, Shannon, Czorny, Brian M, Zeglis, Lynn C, Francesconi, John F, Valliant
Publikováno v:
Journal of medicinal chemistry. 59(20)
A high yield synthesis of a novel, small molecule, bisphosphonate-modified trans-cyclooctene (TCO-BP, 2) that binds to regions of active bone metabolism and captures functionalized tetrazines in vivo, via the bioorthogonal inverse electron demand Die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a88d63eb9ccd6e02f35b60a0fb188a2c
https://pubmed.ncbi.nlm.nih.gov/27676258
https://pubmed.ncbi.nlm.nih.gov/27676258
Autor:
John F. Valliant, Alla Darwish, John W. Babich, Stephanie M. Rathmann, Shawn Hillier, Shannon Czorny, Megan Blacker, John Joyal, Nancy Janzen
Publikováno v:
ACS Medicinal Chemistry Letters. 3:313-316
A new prosthetic group referred to as the triazole appending agent (TAAG) was developed as a means to prepare targeted radioiodine-based molecular imaging and therapy agents. Tributyltin-TAAG and the fluorous analogue were synthesized in high yield u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a0432bca4dd67d4d37773809da4276
https://doi.org/10.1021/ml300003v
https://doi.org/10.1021/ml300003v