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pro vyhledávání: '"Stephanie M. Gorczyca"'
Autor:
Warren M. Mardoum, Stephanie M. Gorczyca, Kathryn E. Regan, Tsai-Chin Wu, Rae M. Robertson-Anderson
Publikováno v:
Frontiers in Physics, Vol 6 (2018)
Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection. However, the impact that crowding has on the dynamics of nucleic acids remains a topic of d
Externí odkaz:
https://doaj.org/article/96aa60ef9c5843929bdacf7aa913c61d
Autor:
Rae M. Robertson-Anderson, Stephanie M. Gorczyca, Kathryn Regan, Tsai Chin Wu, Warren M. Mardoum
Publikováno v:
Frontiers in Physics, Vol 6 (2018)
Frontiers in physics
Frontiers in physics
Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection. However, the impact that crowding has on the dynamics of nucleic acids remains a topic of d
Publikováno v:
Soft Matter. 11:7762-7768
Using single-molecule fluorescence microscopy and particle-tracking techniques, we elucidate the role DNA topology plays in the diffusion and conformational dynamics of crowded DNA molecules. We focus on large (115 kbp), double-stranded ring and line
Publikováno v:
Plastic and Reconstructive Surgery. 120:49S-61S
Magnetic resonance imaging of the breast in the diagnosis of silicone breast implant rupture is widely accepted to be the imaging study of choice for most women. Magnetic resonance imaging in the detection of silicone implant failure has been shown t
Publikováno v:
Biophysical journal. 108(5)
Despite the ubiquity of molecular crowding in living cells, the effects of crowding on the dynamics of genome-sized DNA are poorly understood. Here, we track single, fluorescent-labeled large DNA molecules (11, 115 kbp) diffusing in dextran solutions