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Autor:
Stephanie M Skouras, Virginia Massa, Emily Lurier, Cedric Hubeau, Amy Wang, Xiaozhang Zheng, Kirti Sharma, Dirk Walter, Chris Browne, Michele Mayo, Michael Fitzgerald, Alice McDonald, Jared Gollob, Nello Mainolfi, Anthony Slavin, Veronica Campbell
Publikováno v:
The Journal of Immunology. 208:111.13-111.13
IL-1R/TLR activation plays a central role in the pathophysiology of multiple autoimmune and inflammatory diseases via the Myddosome that is dependent on both the kinase and scaffolding functions of Interleukin-1 receptor associated kinase 4 (IRAK4).