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pro vyhledávání: '"Stephanie LaChapelle"'
Host Cell Invasion by Toxoplasma gondii Is Temporally Regulated by the Host Microtubule Cytoskeleton
Publikováno v:
Eukaryotic Cell. 9:1680-1689
Toxoplasma gondiiis an obligate intracellular protozoan parasite that invades and replicates within most nucleated cells of warm-blooded animals. The basis for this wide host cell tropism is unknown but could be because parasites invade host cells us
Autor:
Allison J. Farrand, Rodney K. Tweten, Arthur E. Johnson, Stephanie LaChapelle, Eileen M. Hotze
Publikováno v:
Proceedings of the National Academy of Sciences. 107:4341-4346
The recognition and binding of cholesterol is an important feature of many eukaryotic, viral, and prokaryotic proteins, but the molecular details of such interactions are understood only for a few proteins. The pore-forming cholesterol-dependent cyto
Publikováno v:
Journal of Biological Chemistry. 284:12719-12726
Intermedilysin (ILY) is an unusual member of the family of cholesterol-dependent cytolysins because it binds to human CD59 (hCD59) rather than directly to cholesterol-rich membranes. Binding of ILY to hCD59 initiates a series of conformational change
Publikováno v:
The Journal of biological chemistry. 284(19)
Intermedilysin (ILY) is an unusual member of the family of cholesterol-dependent cytolysins because it binds to human CD59 (hCD59) rather than directly to cholesterol-rich membranes. Binding of ILY to hCD59 initiates a series of conformational change
Publikováno v:
Cancer Research. 70:760-760
Tumors that express the cell surface enzyme gamma-glutamyl transpeptidase (GGT) have increased resistance to chemotherapy and radiation. GGT cleaves the gamma-glutamyl bond of extracellular glutathione, initiating the cleavage of glutathione into glu