Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephanie L.H. Miller"'
Autor:
Lauren Hughes, Eleanor K. Hanna, Cara R. Damiano, John A. Richey, Gabriel S. Dichter, James W. Bodfish, Stephanie L.H. Miller, Antoinette Sabatino, Alison Rittenberg
Publikováno v:
Social Cognitive and Affective Neuroscience. 9:367-377
Autism spectrum disorders (ASDs) and social anxiety disorder (SAD) are both characterized by social dysfunction, but no study to date has compared neural responses to social rewards in ASDs and SAD. Neural responses during social and non-social rewar
Autor:
Antoinette Sabatino-DiCriscio, Rachel V. Aaron, Stephanie L.H. Miller, Lauren Turner-Brown, Megan Kovac, Jessica L. Kinard, Stephen D. Benning, Noah J. Sasson, Alana Campbell, Gabriel S. Dichter, Eleanor K. Hanna, Cara R. Damiano
Publikováno v:
Journal of autism and developmental disorders. 46(9)
We examined the late positive potential (LPP) event related potential in response to social and nonsocial stimuli from youths 9 to 19 years old with (n = 35) and without (n = 34) ASD. Social stimuli were faces with positive expressions and nonsocial
Background Experience sampling is a powerful method for obtaining ecologically valid data from research participants in real-world contexts. Given the urgent need for innovative and sensitive outcome measures in autism spectrum disorder (ASD) researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85caedcb0abe3c1dec4293741ef8f084
https://europepmc.org/articles/PMC5222541/
https://europepmc.org/articles/PMC5222541/
Publikováno v:
Molecular and Cellular Neuroscience. 35:64-75
The ubiquitin-proteasome system (UPS) actively controls protein dynamics and local abundance via regulated protein degradation. This study investigates UPS' roles in the regulation of postsynaptic function and molecular composition in the Drosophila
Autor:
Lauren Turner-Brown, Megan Kovac, Gabriel S. Dichter, Jessica L. Kinard, Dillon C. Cockrell, Joshua Bizzell, Kaitlyn Dunlap, John Sideris, Eleanor K. Hanna, Cara R. Damiano, Stephanie L.H. Miller
Publikováno v:
Journal of Neurodevelopmental Disorders
Background Previous research has found accumulating evidence for atypical reward processing in autism spectrum disorders (ASD), particularly in the context of social rewards. Yet, this line of research has focused largely on positive social reinforce
Autor:
Jan Domin, Sara Dunn, John P. O'Bryan, Stephanie L.H. Miller, Katy A. Wong, Margaret Das, Negin P. Martin, Erica Scappini, Yun Ju Chen
Publikováno v:
Molecular and cellular biology. 27(22)
While endocytosis attenuates signals from plasma membrane receptors, recent studies suggest that endocytosis also serves as a platform for the compartmentalized activation of cellular signaling pathways. Intersectin (ITSN) is a multidomain scaffoldin
Publikováno v:
The Journal of biological chemistry. 282(13)
Expansion of polyglutamine (polyQ) tracts within proteins underlies a number of neurodegenerative diseases, such as Huntington disease, Kennedy disease, and spinocerebellar ataxias. The resulting mutant proteins are unstable, forming insoluble aggreg
Publikováno v:
Biochemical and biophysical research communications. 328(2)
Epsin is an endocytic adaptor protein involved in the regulation of clathrin-dependent endocytosis. We and others have demonstrated that Epsin is ubiquitylated in cells and requires its ubiquitin interacting motifs (UIMs) for this modification. To fu
Publikováno v:
The Journal of biological chemistry. 279(32)
The ubiquitin-interacting motif (UIM) is a short peptide motif with the dual function of binding ubiquitin and promoting ubiquitylation. This motif is conserved throughout eukaryotes and is present in numerous proteins involved in a wide variety of c
Publikováno v:
Current Biology. (13):1112-1116
The covalent attachment of ubiquitin to proteins is an evolutionarily conserved signal for rapid protein degradation. However, additional cellular functions for ubiquitination are now emerging, including regulation of protein trafficking and endocyto