Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephanie L. Williams-Aziz"'
Autor:
W. Brad Wan, Mark N. Prichard, Shannon Daily, Caroll B. Hartline, Karl Y. Hostetler, James R. Beadle, Nicole L. Kushner, Earl R. Kern, Emma A. Harden, Stephanie L. Williams-Aziz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:3724-3733
Cidofovir (CDV) is an effective therapy for certain human cytomegalovirus (HCMV) infections in immunocompromised patients that are resistant to other antiviral drugs, but the compound is not active orally. To improve oral bioavailability, a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ebe5e9be8f8efa7f094e455472fed6
https://doi.org/10.1128/aac.49.9.3724-3733.2005
https://doi.org/10.1128/aac.49.9.3724-3733.2005
Autor:
Earl R. Kern, Emma A. Harden, Caroll B. Hartline, Stephanie L. Williams-Aziz, Jiri Zemlicka, Shaoman Zhou, Nicole L. Kushner, Mark N. Prichard
We have reported previously that methylenecyclopropane analogs of nucleosides have excellent activity against certain members of the herpesvirus family. A second generation, the 2,2-bis-hydroxymethyl derivatives, were synthesized, and 18 compounds we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12195cce5b601a8b6f0d6516251ee88
https://europepmc.org/articles/PMC549243/
https://europepmc.org/articles/PMC549243/
Autor:
Stephanie L. Williams-Aziz, Caroll B. Hartline, Earl R. Kern, Nicole L. Kushner, Emma A. Harden, Roger J. Brideau
Publikováno v:
Antiviral research. 65(2)
Herpesviruses cause a wide variety of human diseases ranging from cold sores and genital herpes to encephalitis, congenital infections and lymphoproliferative diseases. These opportunistic viruses cause major problems in immunocompromised individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89edccca67f4bce20786c69c0ace6b31
https://pubmed.ncbi.nlm.nih.gov/15708636
https://pubmed.ncbi.nlm.nih.gov/15708636