Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB)

Autor: Peter W. Jurutka, Stephanie L. Suban, John S. Welch, Ankedo Warda, Dena Haddad, Wei Liu, San Raban, Jesse Davidson, Lech J. P. Staniszewski, Ani Minasian, Madleen Khamisi, Sabeeha Mushtaq Reshi, Samir J. Ibrahim, Pamela A. Marshall, Riley Candia, Sanchita Mallick, Joseph W. Ziller, Chang Liu, Ming-Yue Lee, Emma L. Maiorella, Carl E. Wagner, Bradley J. Dawson, Orsola di Martino, Zhela L. Sabir

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12371, p 12371 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22

Five novel analogs of 6-(ethyl)(4-isobutoxy-3-isopropylphenyl)amino)nicotinic acid—or NEt-4IB—in addition to seven novel analogs of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) were prepared and eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025e2ac8b5b2b202f7ed5775f75174f5
https://doi.org/10.3390/ijms222212371