Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephanie L. Rouse"'
Autor:
Jiang Li, Stephanie L. Rouse, Ian R. Matthews, Yesai Park, Yasmin Eltawil, Elliott H. Sherr, Dylan K. Chan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cisplatin is a commonly used chemotherapy agent with a nearly universal side effect of sensorineural hearing loss. The cellular mechanisms underlying cisplatin ototoxicity are poorly understood. Efforts in drug development to prevent or reve
Externí odkaz:
https://doaj.org/article/98976efb3a60470ab2c0b28fd24b4739
Autor:
Dylan K Chan, Stephanie L Rouse
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167850 (2016)
Ca2+ signaling has been implicated in the initial pathophysiologic mechanisms underlying the cochlea's response to acoustic overstimulation. Intracellular Ca2+ signaling (ICS) waves, which occur in glia and retinal cells in response to injury to acti
Externí odkaz:
https://doaj.org/article/4a61a2ce0c7a48d690f8b1123e1f58ae
Racial and Ethnic Disparities in Genetic Testing for Hearing Loss: a Systematic Review and Synthesis
Racial/ethnic disparities in the diagnostic efficacy of genetic testing for hearing loss has been described. These disparities may relate to differences in variant classification between different racial/ethnic groups, which may in turn derive from d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2afa008d6a9fca7fa14c3a35f4a00358
https://doi.org/10.21203/rs.3.rs-484764/v1
https://doi.org/10.21203/rs.3.rs-484764/v1
Autor:
Michelle M Florentine, Stephanie L Rouse, Jihyun Stephans, David Conrad, Josephine Czechowicz, Ian R Matthews, Anna K Meyer, Garani S Nadaraja, Rajan Parikh, Jordan Virbalas, Jacqueline E Weinstein, Dylan K Chan
Understanding racial/ethnic disparities in diagnostic rates of genetic testing is critical for health equity. We sought to understand the extent and cause of racial/ethnic disparities in diagnostic efficacy of comprehensive genetic testing (CGT) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c17f84b3ec4e371251872f0618d48a6
https://doi.org/10.21203/rs.3.rs-482542/v1
https://doi.org/10.21203/rs.3.rs-482542/v1
Autor:
Jordan Virbalas, Josephine A. Czechowicz, Anna K. Meyer, Dylan K. Chan, Ian R. Matthews, Jacqueline E. Weinstein, Michelle M Florentine, David E. Conrad, Jihyun Stephans, Stephanie L Rouse, Garani S. Nadaraja, Rajan Parikh
Publikováno v:
Human genetics. 141(3-4)
Understanding racial and ethnic disparities in diagnostic rates of genetic testing is critical for health equity. We sought to understand the extent and cause of racial and ethnic disparities in diagnostic efficacy of comprehensive genetic testing (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefa45f521de1e51a3739710b0346089
https://pubmed.ncbi.nlm.nih.gov/34515852
https://pubmed.ncbi.nlm.nih.gov/34515852
Racial and ethnic disparities in genetic testing for hearing loss: a systematic review and synthesis
Publikováno v:
Human genetics. 141(3-4)
Racial/ethnic disparities in the diagnostic efficacy of genetic testing for hearing loss have been described. These disparities may relate to differences in variant classification between different racial/ethnic groups, which may, in turn, derive fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c9d6d383d3a8f988694078b6195592
https://pubmed.ncbi.nlm.nih.gov/34494120
https://pubmed.ncbi.nlm.nih.gov/34494120
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Noise-induced hearing loss (NIHL) is a common health concern with significant social, psychological, and cognitive implications. Moderate levels of acoustic overstimulation associated with tinnitus and impaired speech perception cause cochlear synapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6052e63ef96d3303a9c33f82e62184b
https://doi.org/10.1038/s41598-020-75058-w
https://doi.org/10.1038/s41598-020-75058-w
Autor:
Stephanie L Rouse, Conor W. McLaughlin, Jiang Li, Omar Akil, Elliott H. Sherr, Ian R. Matthews, Lawrence R. Lustig, Dylan K. Chan
Publikováno v:
The Journal of clinical investigation, vol 128, iss 11
Hearing loss is a significant public health concern, affecting over 250 million people worldwide. Both genetic and environmental etiologies are linked to hearing loss, but in many cases the underlying cellular pathophysiology is not well understood,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73111e4f543aa7814ff0c1a3283fc1b1
https://doi.org/10.1172/jci97498
https://doi.org/10.1172/jci97498
Autor:
Stephanie L Rouse, Dylan K. Chan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167850 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167850 (2016)
Ca2+ signaling has been implicated in the initial pathophysiologic mechanisms underlying the cochlea's response to acoustic overstimulation. Intracellular Ca2+ signaling (ICS) waves, which occur in glia and retinal cells in response to injury to acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b617c042cfc66261abea57cd90a5a12
https://pubmed.ncbi.nlm.nih.gov/27959894
https://pubmed.ncbi.nlm.nih.gov/27959894
Publikováno v:
Journal of Visualized Experiments.
Gene therapy, used to achieve functional recovery from sensorineural deafness, promises to grant better understanding of the underlying molecular and genetic mechanisms that contribute to hearing loss. Introduction of vectors into the inner ear must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc29f4459cdcdc0e3b3ba347b03966e6
https://doi.org/10.3791/52187
https://doi.org/10.3791/52187