Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephanie L. Reynolds"'
Autor:
Etty N. Benveniste, Andrew T. Holdbrooks, Yudong Liu, Hongwei Qin, Lora L. Yanagisawa, Stephanie L. Reynolds
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(1)
Macrophages participate in both the amplification of inflammation at the time of injury, and downregulation of the inflammatory response to avoid excess tissue damage. These divergent functions of macrophages are dictated by their microenvironment, e
Autor:
Yudong Liu, Hongwei Qin, Stephanie L. Reynolds, Andrew T. Holdbrooks, Lora L. Yanagisawa, Etty N. Benveniste
Publikováno v:
The Journal of Immunology. 189:3439-3448
Macrophages participate in both the amplification of inflammation at the time of injury and downregulation of the inflammatory response to avoid excess tissue damage. These divergent functions of macrophages are dictated by their microenvironment, es
Autor:
Sun Jung Lee, Charles O. Elson, Hongwei Qin, Sandrine Niyongere, Stephanie L. Reynolds, Yingzi Cong, Rosa Serra, Etty N. Benveniste, Lanfang Wang, Casey T. Weaver, Ting Feng, Kevin Roarty
Publikováno v:
The Journal of Immunology. 183:97-105
TGF-β, together with IL-6 and IL-21, promotes Th17 cell development. IL-6 and IL-21 induce activation of STAT3, which is crucial for Th17 cell differentiation, as well as the expression of suppressor of cytokine signaling (SOCS)3, a major negative f
Autor:
Laurie E. Harrington, Andrew T. Holdbrooks, Yudong Liu, Chander Raman, Keun W. Park, Michelle T. Muldowney, Patrizia De Sarno, Wen-I Yeh, Thomas H. Fox, Hongwei Qin, Stephanie L. Reynolds, Lora L. Yanagisawa, Etty N. Benveniste
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(13)
Suppressor of cytokine signaling (SOCS) proteins are feedback inhibitors of the JAK/STAT pathway. SOCS3 has a crucial role in inhibiting STAT3 activation, cytokine signaling, and inflammatory gene expression in macrophages/microglia. To determine the
Autor:
Xiangyu Ma, Brandi J. Baker, Hongwei Qin, Xingang Li, Etty N. Benveniste, Stephanie L. Reynolds
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(9)
Astrocytes have important physiological roles in CNS homeostasis and serve as a bridge between the CNS and immune system. IL-17 and IL-6 are important in many CNS disorders characterized by neuroinflammation. We examined the role of IL-17 on the IL-6
Autor:
Lora L. Yanagisawa, Andrew T. Holdbrooks, Laurie E. Harrington, Etty N. Benveniste, Hongwei Qin, Patrizia De Sarno, Chander Raman, Stephanie L. Reynolds, Braden C. McFarland, Yudong Liu, Wen-I Yeh
Publikováno v:
Cytokine. 56:58
Publikováno v:
The Journal of Immunology. 182:47.21-47.21
Suppressor Of Cytokine Signaling (SOCS) proteins are critical feedback inhibitors of the JAK/STAT signaling pathway and have neuroprotective effects. Recently, several reports have shown that the cytokine IL-27 functions as an inhibitory regulator, a