Výsledky vyhledávání - "Stephanie L. Osborn"

Akademický článek

The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering

Autor: Yvonne Y. Chan, Samantha K. Sandlin, Eric A. Kurzrock, Stephanie L. Osborn

Publikováno v: Biomedicines, Vol 5, Iss 1, p 4 (2017)

Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bla

Externí odkaz: https://doaj.org/article/cc7a1bf0cc154dd097c1166c077fa14d

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Autologous regeneration of blood vessels in urinary bladder matrices provides early perfusion after transplant to the bladder

Autor: Stephanie L. Osborn, Leanna W. Mah, Erica V. Ely, Stefania Ana, Christina Huynh, Naveena S. Ujagar, Serena C. Chan, Philip Hsiao, Jonathan C. Hu, Yvonne Y. Chan, Blaine A. Christiansen, Eric A. Kurzrock

Publikováno v: Journal of Tissue Engineering and Regenerative Medicine. 16:718-731

Large animal testing and clinical trials using bioengineered bladder for augmentation have revealed that large grafts fail due to insufficient blood supply. To address this critical issue, an in vivo staged implant strategy was developed and evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c34d2b375cab221e7fff333b03cc2aa
https://doi.org/10.1002/term.3323

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Using uniaxial tensile testing to evaluate the biomechanical properties of bladder tissue after spinal cord injury in rat model

Autor: Jonathan C. Hu, Stephanie L. Osborn, Presten C. Sanchez, Weichen Xu, Blaine A. Christiansen, Eric A. Kurzrock

Publikováno v: Journal of Biomechanics. 152:111571

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bbc1048e926a99ccb6e5a456ec95969
https://doi.org/10.1016/j.jbiomech.2023.111571

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Inosculation of Blood Vessels Allows Early Perfusion and Vitality of Bladder Grafts—Implications for Bioengineered Bladder Wall

Autor: Michelle So, Eric A. Kurzrock, Jan A. Nolta, Shannon Hambro, Stephanie L. Osborn

Publikováno v: Tissue engineering. Part A, vol 21, iss 11-12

Bioengineered bladder tissue is needed for patients with neurogenic bladder disease as well as for cancer. Current technologies in bladder tissue engineering have been hampered by an inability to efficiently initiate blood supply to the graft, ultima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3e6415959be2975e115244ca20299b
https://doi.org/10.1089/ten.tea.2014.0630

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In Vitro Differentiation and Propagation of Urothelium from Pluripotent Stem Cell Lines

Autor: Eric A. Kurzrock, Stephanie L. Osborn

Publikováno v: Urothelial Carcinoma ISBN: 9781493972333

Bioengineering of bladder tissue, particularly for those patients who have advanced bladder disease, requires a source of urothelium that is healthy, capable of significant proliferation in vitro and immunologically tolerated upon transplant. As plur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db28f61ca0aa36ac5c4771e0943f6580
https://doi.org/10.1007/978-1-4939-7234-0_11

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Functional Role for IκBNS in T Cell Cytokine Regulation As Revealed by Targeted Gene Disruption

Autor: Stephanie L. Osborn, Maki Touma, John E. Connolly, Linda K. Clayton, Derin B. Keskin, Michael J. Grusby, Valeria Antonini, Ellis L. Reinherz, April M. Bobenchik, Manoj Kumar

Publikováno v: The Journal of Immunology. 179:1681-1692

Triggering of the TCR by cognate peptide/MHC ligands induces expression of I kappa BNS, a member of the I kappa B family of NF-kappaB inhibitors whose expression is associated with apoptosis of immature thymocytes. To understand the role of I kappa B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d1ac572d8fb8ffad81b48cb538b93d
https://doi.org/10.4049/jimmunol.179.3.1681

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Constitutive Phosphorylation Mutation in Fas-associated Death Domain (FADD) Results in Early Cell Cycle Defects

Autor: Sue J Sohn, Stephanie L. Osborn, Astar Winoto

Publikováno v: Journal of Biological Chemistry. 282:22786-22792

Fas-associated death domain (FADD) is an adaptor molecule for the death receptor subfamily of the tumor necrosis factor receptor superfamily, but it is also required for cell proliferation. Cell cycle-specific regulation of FADD phosphorylation plays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345741b7ce0b782794c358d31f1441d5
https://doi.org/10.1074/jbc.m703163200

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Production of urothelium from pluripotent stem cells for regenerative applications

Autor: Eric A. Kurzrock, Stephanie L. Osborn

Publikováno v: Current urology reports, vol 16, iss 1
Osborn, SL; & Kurzrock, EA. (2015). Production of Urothelium from Pluripotent Stem Cells for Regenerative Applications. Current Urology Reports, 16(1), 1-7. doi: 10.1007/s11934-014-0466-6. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/8w6617gf
Current Urology Reports, vol 16, iss 1
Osborn, SL; & Kurzrock, EA. (2015). Production of urothelium from pluripotent stem cells for regenerative applications. Current urology reports, 16(1), 466. doi: 10.1007/s11934-014-0466-6. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/52w581vw

© 2014, Springer Science+Business Media New York. As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Plu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a97b1b3986b266da67cb233899f9f9
https://escholarship.org/uc/item/52w581vw

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