Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie L. Murphy"'
Autor:
Erik A. Koppes, Bethany K. Redel, Marie A. Johnson, Kristen J. Skvorak, Lina Ghaloul-Gonzalez, Megan E. Yates, Dale W. Lewis, Susanne M. Gollin, Yijen L. Wu, Shawn E. Christ, Martine Yerle, Angela Leshinski, Lee D. Spate, Joshua A. Benne, Stephanie L. Murphy, Melissa S. Samuel, Eric M. Walters, Sarah A. Hansen, Kevin D. Wells, Uta Lichter-Konecki, Robert A. Wagner, Joseph T. Newsome, Steven F. Dobrowolski, Jerry Vockley, Randall S. Prather, Robert D. Nicholls
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental disabilities. Dietary phenylalanine (Phe) restriction prevents the most deleteri
Externí odkaz:
https://doaj.org/article/25a4c7bc5404441d96bc2b097f4c68db
Autor:
Bethany K Redel, Benjamin P Beaton, Lee D Spate, Joshua A Benne, Stephanie L Murphy, Chad W O’Gorman, Anna M Spate, Randall S Prather, Kevin D Wells
Publikováno v:
BioTechniques, Vol 64, Iss 3, Pp 118-124 (2018)
Production of Cas9 mRNA in vitro typically requires the addition of a 5´ cap and 3´ polyadenylation. A plasmid was constructed that harbored the T7 promoter followed by the EMCV IRES and a Cas9 coding region. We hypothesized that the use of the met
Externí odkaz:
https://doaj.org/article/0c50dbd04e8e4a50b5173c1f244c4e26
Autor:
Robert Wagner, Kevin D. Wells, Steven F. Dobrowolski, Susanne M. Gollin, Robert D. Nicholls, Yijen L. Wu, Marie A. Johnson, Eric M. Walters, Erik A. Koppes, Sarah A. Hansen, M Yerle, Shawn E. Christ, Dale W. Lewis, Melissa Samuel, Joseph T. Newsome, Kristen J. Skvorak, Megan E. Yates, Lina Ghaloul-Gonzalez, Randall S. Prather, Uta Lichter-Konecki, Stephanie L. Murphy, Lee D. Spate, Joshua A. Benne, Jerry Vockley, Bethany K. Redel, Angela Leshinski
Publikováno v:
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2020, 5 (20), ⟨10.1172/jci.insight.141523⟩
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight, American Society for Clinical Investigation, 2020, 5 (20), ⟨10.1172/jci.insight.141523⟩
JCI Insight, Vol 5, Iss 20 (2020)
Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental disabilities. Dietary phenylalanine (Phe) restriction prevents the most deleteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85254df3b5697eb1b6ace05dcedc976c
https://hal.inrae.fr/hal-03158896
https://hal.inrae.fr/hal-03158896
Autor:
Shirley Rojas Salazar, Tieming Ji, Jonathan A. Green, Bethany R. Mordhorst, Susanta K. Behura, Randall S. Prather, Martin Schauflinger, Kevin D. Wells, Stephanie L. Murphy
Publikováno v:
Cellular Reprogramming
The Warburg effect is characterized by decreased mitochondrial oxidative phosphorylation and increased glycolytic flux in adequate oxygen. The preimplantation embryo has been described to have characteristics of the Warburg effect, including similar
Autor:
Clifton N. Murphy, Stephanie L. Murphy, Renee M. Ross, Jonathan A. Green, Kevin D. Wells, Bethany K. Redel, Lee D. Spate, Raissa F. Cecil, Joshua A. Benne, Bethany R. Mordhorst, Melissa Samuel, Randall S. Prather
Publikováno v:
Molecular Reproduction and Development. 85:290-302
Somatic cell nuclear transfer is a valuable technique for the generation of genetically engineered animals, however, the efficiency of cloning in mammalian species is low (1-3%). Differentiated somatic cells commonly used in nuclear transfer utilize
Autor:
Randall S. Prather, Stephanie L. Murphy, Bethany K. Redel, Chad O'Gorman, Benjamin P. Beaton, Lee D. Spate, Anna Spate, Joshua A. Benne, Kevin D. Wells
Publikováno v:
BioTechniques. 64:118-124
Production of Cas9 mRNA in vitro typically requires the addition of a 5´ cap and 3´ polyadenylation. A plasmid was constructed that harbored the T7 promoter followed by the EMCV IRES and a Cas9 coding region. We hypothesized that the use of the met
Autor:
Tieming Ji, Shirley Rojas Salazar, Rence M Ross, Bethany R. Mordhorst, Kevin D. Wells, Stephanie L. Murphy, Susanta K. Behura, Melissa Samuel, Randall S. Prather, Jonathan A. Green
Publikováno v:
Cellular Reprogramming
The Warburg effect is a metabolic phenomenon characterized by increased glycolytic activity, decreased mitochondrial oxidative phosphorylation, and the production of lactate. This metabolic phenotype is characterized in rapidly proliferative cell typ
Autor:
Kevin D. Wells, Stephanie L. Murphy, Peter Sutovsky, Jonathan A. Green, Bethany R. Mordhorst, Martin Schauflinger, Karl Kerns, Michal Zigo, Randall S. Prather, Renee M. Ross
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
A metabolic phenomenon known as the Warburg effect has been characterized in certain cancerous cells, embryonic stem cells, and other rapidly proliferative cell types. Previously, our attempts to induce a Warburg-like state pharmaceutically via CPI-6
Autor:
Clifton N. Murphy, Kristin M. Whitworth, Melissa Samuel, Jürgen A. Richt, Lee D. Spate, Stephanie L. Murphy, Joshua A. Benne, Kevin D. Wells, Eric M. Walters, Randall S. Prather
Publikováno v:
Transgenic Research. 26:97-107
The CRISPR/Cas9 genome editing tool has increased the efficiency of creating genetically modified pigs for use as biomedical or agricultural models. The objectives were to determine if DNA editing resulted in a delay in development to the blastocyst
Publikováno v:
Encyclopedia of Soil Science, Third Edition ISBN: 9781315161860
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be1702c28225614ae581f6158fb46d2c
https://doi.org/10.1081/e-ess3-120042775
https://doi.org/10.1081/e-ess3-120042775