Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephanie L. Lomonaco"'
Autor:
Cunli Xiang, Sandra A. Rempel, Tom Mikkelsen, Stephanie L. Lomonaco, Wei Jiang, Chaya Brodie, Nancy Lemke, Susan Finniss, Hae Kyung Lee
Publikováno v:
Neuro-Oncology. 13:857-865
We studied the effect of the integrin inhibitor cilengitide in glioma cells. Cilengitide induced cell detachment and decreased cell viability, and induction of autophagy followed by cell apoptosis. In addition, cilengitide decreased the cell renewal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239bf6c9d782447d0f897de81557df11
https://doi.org/10.1093/neuonc/nor073
https://doi.org/10.1093/neuonc/nor073
Autor:
Cunli Xiang, Susan Finniss, Stephanie L. Lomonaco, Felix Umansky, Tom Mikkelsen, Ana C. deCarvalho, Chaya Brodie, Steven N. Kalkanis
Publikováno v:
International Journal of Cancer. 125:717-722
Malignant gliomas are characterized by a short median survival which is largely impacted by the resistance of these tumors tochemo- and radiotherapy. Recent studies suggest that a small subpopulation of cancer stem cells, which are highly resistant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7668abec2b27a0bb5ec1a684036c40a
https://doi.org/10.1002/ijc.24402
https://doi.org/10.1002/ijc.24402
Publikováno v:
DNA and Cell Biology. 28:285-294
Many anticancer drugs target the genomic DNA of cancer cells by generating DNA damage and inducing apoptosis. DNA repair protects cells against DNA damage-induced apoptosis. Although the mechanisms of DNA repair and apoptosis have been extensively st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e675e58a414282b5381b28472d9997a1
https://doi.org/10.1089/dna.2008.0815
https://doi.org/10.1089/dna.2008.0815
Autor:
Hana Okhrimenko, Stephanie L. Lomonaco, Cunli Xiang, Chaya Brodie, Yehuda Brody, Hae Kyung Lee, Michal Blass, Peter M. Blumberg, Susan Finniss, Sarit Kahana
Publikováno v:
Journal of Biological Chemistry. 283:17731-17739
The mechanism underlying the important role of protein kinase Cδ (PKCδ) in the apoptotic effect of etoposide in glioma cells is incompletely understood. Here, we examined the role of PKCδ in the activation of Erk1/2 by etoposide. We found that eto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05fcfdfa9e553b8a7553a6f11e17b26a
https://doi.org/10.1074/jbc.m801727200
https://doi.org/10.1074/jbc.m801727200
Autor:
Chaya Brodie, Stephanie L. Lomonaco
Publikováno v:
Protein Kinase C in Cancer Signaling and Therapy ISBN: 9781607615422
PKCd, a member of the novel PKC family, has been widely implicated as mediator of apoptosis in response to phorbol esters and chemotherapeutic agents, and it is differentially expressed in various human cancer types. A characteristic of PKCd is that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e35a35af3e7c5c0e05d22adb10fc3a
https://doi.org/10.1007/978-1-60761-543-9_22
https://doi.org/10.1007/978-1-60761-543-9_22
Autor:
Stephanie L, Lomonaco, Sarit, Kahana, Michal, Blass, Yehuda, Brody, Hana, Okhrimenko, Cunli, Xiang, Susan, Finniss, Peter M, Blumberg, Hae-Kyung, Lee, Chaya, Brodie
Publikováno v:
The Journal of biological chemistry. 283(25)
The mechanism underlying the important role of protein kinase Cdelta (PKCdelta) in the apoptotic effect of etoposide in glioma cells is incompletely understood. Here, we examined the role of PKCdelta in the activation of Erk1/2 by etoposide. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acdd60d955519ce5dd311724da04ef45
https://pubmed.ncbi.nlm.nih.gov/18434324
https://pubmed.ncbi.nlm.nih.gov/18434324