Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Stephanie L. Leal"'
Autor:
Taylor O. Phillips, Madelyn Castro, Rishi K. Vas, Lorena A. Ferguson, Amritha Harikumar, Stephanie L. Leal
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
IntroductionWhile antidepressants are one of the first-line treatments for depression, the mechanisms underlying antidepressant action are unclear. Furthermore, the extent to which antidepressants impact emotional and cognitive dysfunction in depress
Externí odkaz:
https://doaj.org/article/d1e9c864cc3c4202955d310f7aa8a9c1
Autor:
Jie Zheng, Kristopher L. Anderson, Stephanie L. Leal, Avgusta Shestyuk, Gultekin Gulsen, Lilit Mnatsakanyan, Sumeet Vadera, Frank P. K. Hsu, Michael A. Yassa, Robert T. Knight, Jack J. Lin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Amygdala and hippocampus are involved in processing motivationally salient stimuli but the precise circuit dynamics of the interaction is not understood. Here the authors show that in response to fearful faces in humans, theta/alpha oscillations in t
Externí odkaz:
https://doaj.org/article/8db1d32d5afa44fb9aa6a212f860d542
Retirement is a period of significant change, as older adults transition from a lifetime of work to unstructured leisure time. This sudden shift in activity may have drastic consequences on cognition and disease risk. Retirement has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e74b601727f384a8d9fba9f95a1f7eb9
https://doi.org/10.31234/osf.io/46efu
https://doi.org/10.31234/osf.io/46efu
Difficulty remembering faces and names is a common struggle for many people and gets more difficult as we age. Subtle changes in appearance from day to day, common facial characteristics across individuals, and overlap of names may contribute to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef4f9f9f23da5db371dc15035de7cdc
https://doi.org/10.31219/osf.io/5hb7v
https://doi.org/10.31219/osf.io/5hb7v
Autor:
Taylor Phillips, Madelyn Castro, Rishi Vas, Lorena A. Ferguson, Amritha Harikumar, Stephanie L Leal
Background: Depression is associated with general memory impairment as well as a negativity bias, where negative experiences are better remembered. One potential mechanism underlying the negativity bias in depression could be pattern separation, a hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5634259e72eb4ae107b147f16a008148
https://doi.org/10.31234/osf.io/xwt4j
https://doi.org/10.31234/osf.io/xwt4j
Publikováno v:
eLife, Vol 6 (2017)
The amyloid hypothesis suggests that beta-amyloid (Aβ) deposition leads to alterations in neural function and ultimately to cognitive decline in Alzheimer’s disease. However, factors that underlie Aβ deposition are incompletely understood. One pr
Externí odkaz:
https://doaj.org/article/8fa27c6bbee94fffbd7b6d1706ad93da
Autor:
Brandon K. Hayes, Amritha Harikumar, Lorena A. Ferguson, Eva E. Dicker, Bryan Denny, Stephanie L Leal
Stressful experiences are unavoidable, yet tactics can be employed to mitigate their impact on our cognition and well-being. Individuals with depression show dysfunctional emotion regulation, general episodic memory deficits, and a negativity bias, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e60f28da0ba29c55be494c3e37ece1ab
https://doi.org/10.31234/osf.io/6jn5w
https://doi.org/10.31234/osf.io/6jn5w
Autor:
Jordan Matthew Ngo, Aida Husain, Debashis Sahoo, Pradipta Ghosh, Deepali Bhandari, Stephanie L. Leal, Clariss Limso, Peter Nguyen
Publikováno v:
FEBS Lett
Cell surface translocation of the chaperone glucose-regulated protein 78 kDa (GRP78) is a key event that promotes cancer cell survival during endoplasmic reticulum (ER) stress. Here, we identify Gα-interacting vesicle-associated protein (GIV) - an e
Autor:
Michael A. Yassa, John Janecek, Steven J. Granger, Stephanie L. Leal, Hal S. Stern, Liv McMillan, Myra S. Larson
Publikováno v:
Neurobiol Learn Mem
Alterations in white matter integrity have been demonstrated in a number of psychiatric disorders involving emotional disruptions. One such pathway - the uncinate fasciculus - connects the orbitofrontal cortex (OFC) to the medial temporal lobes (MTL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1064f20358b32de57731ee88d77a2f3
https://escholarship.org/uc/item/8tm904hj
https://escholarship.org/uc/item/8tm904hj
Autor:
E. Lydia Wu-Chung, Stephanie L. Leal, Bryan T. Denny, Samantha L. Cheng, Christopher P. Fagundes
Publikováno v:
Neurosci Biobehav Rev
Accumulating research suggests that stressful life events, especially those that threaten close intimate bonds, are associated with an increased risk of dementia. Grieving the loss of a spouse, whether in the form of caregiving or after the death, ra