Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephanie L. Courchesne"'
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16753 (2011)
Disruptions in axonal transport have been implicated in a wide range of neurodegenerative diseases. Cramping 1 (Cra1/+) and Legs at odd angles (Loa/+) mice, with hypomorphic mutations in the dynein heavy chain 1 gene, which encodes the ATPase of the
Externí odkaz:
https://doaj.org/article/abbbc5293cf645a0ae11be11ed4deecf
Publikováno v:
The Journal of Neuroscience. 31:1624-1634
Small fiber sensory neuropathy is a common disorder in which progressive degeneration of small-diameter nociceptors causes decreased sensitivity to thermal stimuli and painful sensations in the extremities. In the majority of patients, the cause of s
Autor:
Heather M. Heerssen, Christoph Karch, Fiona L. Watson, Michael E. Greenberg, Tae Kyung Kim, Rosalind A. Segal, Stephanie L. Courchesne, Maria F. Pazyra-Murphy, Aymeric Hans, Katharina E. Cosker
Publikováno v:
The Journal of Neuroscience. 29:6700-6709
Survival and maturation of dorsal root ganglia sensory neurons during development depend on target-derived neurotrophins. These target-derived signals must be transmitted across long distances to alter gene expression. Here, we address the possibilit
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16753 (2011)
PLoS ONE
PLoS ONE
Disruptions in axonal transport have been implicated in a wide range of neurodegenerative diseases. Cramping 1 (Cra1/+) and Legs at odd angles (Loa/+) mice, with hypomorphic mutations in the dynein heavy chain 1 gene, which encodes the ATPase of the
Neurons extend axonal processes over long distances, necessitating efficient transport mechanisms to convey target-derived neurotrophic survival signals from remote distal axons to cell bodies. Retrograde transport, powered by dynein motors, supplies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f0eeaf04e544b1117773b3a27aebad
https://europepmc.org/articles/PMC2693191/
https://europepmc.org/articles/PMC2693191/
Autor:
Meihua Deng, Robert Spoelgen, Mirjam Koker, Toshifumi Matsui, Michael C. Irizarry, Stefan F. Lichtenthaler, Christine A F Von Arnim, Hisatomo Kowa, Stephanie L. Courchesne, Ithan D. Peltan, Bradley T. Hyman
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(39)
The beta-amyloid (Abeta) precursor protein (APP) is cleaved sequentially by beta-site of APP-cleaving enzyme (BACE) and gamma-secretase to release the Abeta peptides that accumulate in plaques in Alzheimer's disease (AD). GGA1, a member of the Golgi-
Autor:
Julio J. Ramirez, Sean Wentworth, Winona E. Poulton, Stephanie L. Courchesne, David Campbell, Kindiya D. Geghman, Jennifer Swails, Cole Barton
Publikováno v:
Neurobiology of learning and memory. 87(2)
Entorhinal cortex lesions induce significant reorganization of several homotypic and heterotypic inputs to the hippocampus. This investigation determined whether surviving heterotypic inputs after bilateral entorhinal lesions would support the acquis
GGA1 overexpression alters trafficking and subcellular distribution of the amyloid precursor protein
Autor:
Meihua Deng, Ithan D. Peltan, B. T. Hyman, Michael C. Irizarry, Stefan F. Lichtenthaler, Stephanie L. Courchesne, C. A. F. von Arnim
Publikováno v:
Aktuelle Neurologie. 32