Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephanie L. C. Scofield"'
Autor:
Patsy R. Thrasher, Krishna Singh, Suman Dalal, Jonathan M. Peterson, Christopher R. Daniels, Mahipal Singh, Stephanie L. C. Scofield, Kristina A. Lim
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 316:H617-H628
β-Adrenergic receptor (β-AR) stimulation increases extracellular levels of ubiquitin (UB) in myocytes, and exogenous UB decreases β-AR-stimulated myocyte apoptosis and myocardial fibrosis. Here, we hypothesized that exogenous UB modulates the infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8249b9e6eaa9c7680761e7c0b6224a
https://doi.org/10.1152/ajpheart.00654.2018
https://doi.org/10.1152/ajpheart.00654.2018
Autor:
Jonathan A. Millard, Christopher R. Daniels, Mahipal Singh, Krishna Singh, Suman Dalal, Stephanie L. C. Scofield
Publikováno v:
Life Sciences. 211:8-16
Aims β-adrenergic receptor (β-AR) stimulation increases extracellular levels of ubiquitin (UB), and exogenous UB plays an important role in β-AR-stimulated myocardial remodeling with effects on heart function, fibrosis and myocyte apoptosis. Cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfb2fd1d5518cd831cfabe42c48cc60
https://doi.org/10.1016/j.lfs.2018.09.012
https://doi.org/10.1016/j.lfs.2018.09.012
Autor:
Patsy R. Thrasher, Mahipal Singh, Krishna Singh, Claire C. Crawford, Stephanie L. C. Scofield, Suman Dalal
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 315(1)
Ataxia telangiectasia mutated kinase (ATM) is activated in response to DNA damage. We have previously shown that ATM plays a critical role in myocyte apoptosis and cardiac remodeling after myocardial infarction (MI). Here, we tested the hypothesis th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c40a3675e7ffc8efe74f7b8ef2ddaab
https://pubmed.ncbi.nlm.nih.gov/29750568
https://pubmed.ncbi.nlm.nih.gov/29750568
Publikováno v:
Journal of Visualized Experiments.
Many animal models have been established for the study of myocardial remodeling and heart failure due to its status as the number one cause of mortality worldwide. In humans, a pathologic occlusion forms in a coronary artery and reperfusion of that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d7a25d35c8d9e0bda3d99ad51ae838
https://doi.org/10.3791/54814
https://doi.org/10.3791/54814
Autor:
Christopher R. Daniels, Cerrone R. Foster, Stephanie L. C. Scofield, Mahipal Singh, Suman Dalal, Krishna Singh, Patsy R. Thrasher, Laura L. Daniel
Ataxia telangiectasia-mutated kinase (ATM), a cell cycle checkpoint protein, is activated in response to DNA damage and oxidative stress. We have previously shown that ATM deficiency is associated with increased apoptosis and fibrosis and attenuation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29daa0ec2d5361403495805ed50afa9
https://europepmc.org/articles/PMC5005283/
https://europepmc.org/articles/PMC5005283/
