Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stephanie L Timmerman"'
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3242 (2007)
A single internal ribosomal entry site (IRES) in conjunction with IRES transactivating factors (ITAFs) is sufficient to recruit the translational machinery to a eukaryotic mRNA independent of the cap structure. However, we demonstrate that the mouse
Externí odkaz:
https://doaj.org/article/3cc17d664c6c472ba033c889a0858f29
Publikováno v:
Nucleic Acids Research
Most eukaryotic mRNAs are monocistronic and translated by cap-dependent initiation. LINE-1 RNA is exceptional because it is naturally dicistronic, encoding two proteins essential for retrotransposition, ORF1p and ORF2p. Here, we show that sequences u
Publikováno v:
BMC Molecular Biology, Vol 9, Iss 1, p 89 (2008)
BMC Molecular Biology
BMC Molecular Biology
Background Regulating synthesis of the Fragile X gene (FMR1) product, FMRP alters neural plasticity potentially through its role in the microRNA pathway. Cap-dependent translation of the FMR1 mRNA, a process requiring ribosomal scanning through the 5
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 9, p e3242 (2007)
PLoS ONE, Vol 3, Iss 9, p e3242 (2007)
A single internal ribosomal entry site (IRES) in conjunction with IRES transactivating factors (ITAFs) is sufficient to recruit the translational machinery to a eukaryotic mRNA independent of the cap structure. However, we demonstrate that the mouse