Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Stephanie L Moon"'
Autor:
Stephanie L Moon, Jeffrey G Blackinton, John R Anderson, Mary K Dozier, Benjamin J T Dodd, Jack D Keene, Carol J Wilusz, Shelton S Bradrick, Jeffrey Wilusz
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004708 (2015)
We demonstrate that both Hepatitis C virus (HCV) and Bovine Viral Diarrhea virus (BVDV) contain regions in their 5' UTRs that stall and repress the enzymatic activity of the cellular 5'-3' exoribonuclease XRN1, resulting in dramatic changes in the st
Externí odkaz:
https://doaj.org/article/ccc5df6b60bf40dabcbfb5732937f2a6
Publikováno v:
eLife, Vol 3 (2014)
Dengue virus is a growing global health threat. Dengue and other flaviviruses commandeer the host cell’s RNA degradation machinery to generate the small flaviviral RNA (sfRNA), a noncoding RNA that induces cytopathicity and pathogenesis. Host cell
Externí odkaz:
https://doaj.org/article/3e1986a94ca6477582777c03339950e3
Autor:
Stephanie L Moon, Jeffrey Wilusz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003762 (2013)
Externí odkaz:
https://doaj.org/article/ee063ad035904201a2a22da254a30bdc
Autor:
Benjamin Dodd, Stephanie L. Moon
Publikováno v:
Dystonia, Vol 2 (2023)
Dystonia is a progressive neurological motor disease with few treatment options and no cure. This review synthesizes the results of recent studies that implicate protein kinase R in mediating the molecular mechanisms of dystonia pathogenesis. Mutatio
Externí odkaz:
https://doaj.org/article/530c370d90a54c888aae274cacc490eb
Autor:
Noah S. Helton, Stephanie L. Moon
Publikováno v:
Biochemical Society Transactions. 50:1715-1724
Maintenance of proteostasis is of utmost importance to cellular viability and relies on the coordination of many post-transcriptional processes to respond to stressful stimuli. Stress granules (SGs) are RNA–protein condensates that form after trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42172e4e692dfd1154aaa444588a6367
https://doi.org/10.1042/bst20220549
https://doi.org/10.1042/bst20220549
Autor:
Alyssa M, English, Stephanie L, Moon
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2428
The attenuation of global translation is a critical outcome of the integrated stress response (ISR). Consequently, it is important to effectively detect and measure protein synthesis in studies seeking to evaluate the ISR. This chapter details two me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bc0a87a7685e9a4257e1c47755f2cd4
https://pubmed.ncbi.nlm.nih.gov/35171473
https://pubmed.ncbi.nlm.nih.gov/35171473
Autor:
Alyssa M. English, Stephanie L. Moon
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82709081e5f1cef9aa9158a0babdfd12
https://doi.org/10.1007/978-1-0716-1975-9_4
https://doi.org/10.1007/978-1-0716-1975-9_4
Publikováno v:
WIREs RNA. 13
The integrated stress response (ISR) is a conserved mechanism by which eukaryotic cells remodel gene expression to adapt to intrinsic and extrinsic stressors rapidly and reversibly. The ISR is initiated when stress-activated protein kinases phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7ed1c2801a30583373f32ae35567cc
https://doi.org/10.1002/wrna.1689
https://doi.org/10.1002/wrna.1689
Autor:
Tatsuya Morisaki, Roy Parker, Timothy J. Stasevich, Stephanie L. Moon, Kenneth Lyon, Anthony Khong
Publikováno v:
Nature cell biology
Ribonucleoprotein (RNP) granules are non-membrane-bound organelles that have critical roles in the stress response1,2, maternal messenger RNA storage3, synaptic plasticity4, tumour progression5,6 and neurodegeneration7-9. However, the dynamics of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da87b6fccc877dc91e060df5ddb8c0ea
https://doi.org/10.1038/s41556-018-0263-4
https://doi.org/10.1038/s41556-018-0263-4
Publikováno v:
The Journal of Cell Biology
Moon et al., demonstrate a new role for ribosome-associated quality control (RQC) factors in mediating mRNA release from ribosomes during stress to promote their localization to stress granules.
Stress granules are dynamic assemblies of proteins
Stress granules are dynamic assemblies of proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5a7331d9dbeacdadb3cc3a31a06a60