Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephanie L Battle"'
Autor:
Bo Yu, Naresh Doni Jayavelu, Stephanie L Battle, Jessica C Mar, Timothy Schimmel, Jacques Cohen, R David Hawkins
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241698 (2020)
Oocyte maturation is a coordinated process that is tightly linked to reproductive potential. A better understanding of gene regulation during human oocyte maturation will not only answer an important question in biology, but also facilitate the devel
Externí odkaz:
https://doaj.org/article/09616ac32edb4f0e9504bb5cdaa72d23
Publikováno v:
Frontiers in Plant Science, Vol 5 (2014)
The small phenolic compound salicylic acid (SA) plays a critical role in plant defense against broad-spectrum of pathogens. The phosphate transporter gene PHT4;1 was previously shown to affect SA-mediated defense and its expression is regulated by th
Externí odkaz:
https://doaj.org/article/93006ec94bb04334be9e39037925415c
Autor:
Yun Soo Hong, Stephanie L. Battle, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Jiaqi Xie, Nathan Pankratz, Nicole J. Lake, Monkol Lek, Jerome I. Rotter, Stephen S. Rich, Charles Kooperberg, Alex P. Reiner, Paul L. Auer, Nancy Heard-Costa, Chunyu Liu, Meng Lai, Joanne M. Murabito, Daniel Levy, Megan L. Grove, Alvaro Alonso, Richard Gibbs, Shannon Dugan-Perez, Lukasz P. Gondek, Eliseo Guallar, Dan E. Arking
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 s to 10,000 s copies in so
Externí odkaz:
https://doaj.org/article/8424ec81fd124e7695c09c8c5db1a8bc
Autor:
Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24975- (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a downstream modifier of n
Externí odkaz:
https://doaj.org/article/3a074f5bc5b844fb908962fcae463ee2
Publikováno v:
Epigenetics, Vol 14, Iss 8, Pp 780-790 (2019)
Assisted reproductive technologies are known to alter the developmental environment of gametes and early embryos during the most dynamic period of establishing the epigenome. This may result in the introduction of errors during active DNA methylation
Externí odkaz:
https://doaj.org/article/819c8eaf94fd4369b2ee3afdac51e24a
Autor:
Stephanie L. Battle, Naresh Doni Jayavelu, Robert N. Azad, Jennifer Hesson, Faria N. Ahmed, Eliah G. Overbey, Joseph A. Zoller, Julie Mathieu, Hannele Ruohola-Baker, Carol B. Ware, R. David Hawkins
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1129-1144 (2019)
Summary: During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (prime
Externí odkaz:
https://doaj.org/article/a4701e94f0d8402a95a19165a7d8c1db
Autor:
Kalyan K. Pasumarthy, Naresh Doni Jayavelu, Lotta Kilpinen, Colin Andrus, Stephanie L. Battle, Matti Korhonen, Petri Lehenkari, Riikka Lund, Saara Laitinen, R. David Hawkins
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 999-1015 (2017)
Human bone marrow stromal cells, or mesenchymal stem cells (BM-MSCs), need expansion prior to use as cell-based therapies in immunological and tissue repair applications. Aging and expansion of BM-MSCs induce epigenetic changes that can impact therap
Externí odkaz:
https://doaj.org/article/80d7d5cb651d41fb81bde32a77bc6257
Autor:
Nicole J. Lake, Wei Liu, Stephanie L. Battle, Kristen M. Laricchia, Grace Tiao, Daniela Puiu, Alison G. Compton, Shannon Cowie, John Christodoulou, David R. Thorburn, Hongyu Zhao, Dan E. Arking, Shamil R. Sunyaev, Monkol Lek
Mitochondrial DNA (mtDNA) has an important, yet often overlooked, role in health and disease. Constraint models quantify the removal of deleterious variation from the population by selection, representing a powerful tool for identifying genetic varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f932b4885692cdddec5d7f0db2a2e5fb
https://doi.org/10.1101/2022.12.16.520778
https://doi.org/10.1101/2022.12.16.520778
Autor:
Stephanie L Battle, Yun Soo Hong, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Nathan Pankratz, Nicole J Lake, Monkol Lek, Eliseo Guallar, Dan E Arking
SummaryMitochondria are involved in energetic, biosynthetic, and homeostatic processes in eukaryotic cells. Mitochondria carry their own circular genome and disruption of the quantity or quality of mitochondrial genome is associated with various agin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8facc2e44c3e6625eee1b4c1433d75a7
https://doi.org/10.1101/2022.09.20.22280151
https://doi.org/10.1101/2022.09.20.22280151
Autor:
Charles E. Newcomb, Hélène C. F. Côté, Anthony Y.Y. Hsieh, Hailey L. Chapman, Stephanie Y. Yang, Stephanie L. Battle, Dan E. Arking
Mitochondrial DNA copy number (mtDNA-CN) is a proxy for mitochondrial function and has been of increasing interest to the mitochondrial research community. There are a number of ways to measure mtDNA-CN, ranging from qPCR to whole genome sequencing [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aed64b5646478fc4313505a7f4123da
https://doi.org/10.1101/2021.10.11.463983
https://doi.org/10.1101/2021.10.11.463983