Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephanie Kourula"'
Autor:
Sarah Campion, Amy Inselman, Belinda Hayes, Costanza Casiraghi, David Joseph, Fabrizio Facchinetti, Fabrizio Salomone, Georg Schmitt, Julia Hui, Karen Davis-Bruno, Karen Van Malderen, LaRonda Morford, Luc De Schaepdrijver, Lutz Wiesner, Stephanie Kourula, Suna Seo, Susan Laffan, Vijay Urmaliya, Connie Chen
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 4 (2022)
Increased research to improve preclinical models to inform the development of therapeutics for neonatal diseases is an area of great need. This article reviews five common neonatal diseases – bronchopulmonary dysplasia, retinopathy of prematurity,
Externí odkaz:
https://doaj.org/article/2b780bb945cf480c8f579328eb912ef4
Autor:
Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The enterotoxins TcdA and TcdB induce cytotoxicity of epithelial cells during Clostridium difficile infection. Here the authors show that bacterial induced epithelial cell death occurs via activation of caspases 3 and 7, resulting in apoptotic cell d
Externí odkaz:
https://doaj.org/article/708354e64dcb42588aa6882947904dbf
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 161 (2021)
The increasing prevalence of colonic diseases calls for a better understanding of the various colonic drug absorption barriers of colon-targeted formulations, and for reliable in vitro tools that accurately predict local drug disposition. In vivo rel
Externí odkaz:
https://doaj.org/article/fbf599558ae949e7b775962b8cae1475
Autor:
Stephanie Kourula, Merel Derksen, Ferran Jardi, Sophie Jonkers, Marjolein van Heerden, Peter Verboven, Veronique Theuns, Stijn Van Asten, Tinne Huybrechts, Annett Kunze, Ewa Frazer-Mendelewska, Ka Wai Lai, René Overmeer, Jamie Lee Roos, Robert G.J. Vries, Sylvia F. Boj, Mario Monshouwer, Farzin Pourfarzad, Jan Snoeys
Publikováno v:
European Journal of Pharmaceutical Sciences. :106481
Autor:
Farzaneh Ghazavi, Jelle Huysentruyt, Jordy De Coninck, Stephanie Kourula, Sofie Martens, Behrouz Hassannia, Tim Wartewig, Tatyana Divert, Ria Roelandt, Bastian Popper, Andreas Hiergeist, Peter Tougaard, Tom Vanden Berghe, Marie Joossens, Geert Berx, Nozomi Takahashi, Adam Wahida, Peter Vandenabeele
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proc. Natl. Acad. Sci. U.S.A. 119:e2024508119 (2022)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Proc. Natl. Acad. Sci. U.S.A. 119:e2024508119 (2022)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Apoptosis is widely believed to be crucial for epithelial cell death and shedding in the intestine, thereby shaping the overall architecture of the gastrointestinal tract, but also regulating tolerance induction, pinpointing a role of apoptosis intes
Autor:
Benjamin K. Cline, Lucie Ludvíková, Lucie Muchová, Petr Klán, Hendrik J. Vreman, Libor Vítek, David K. Stevenson, Stephanie Kourula, Ronald J. Wong, Jana Jašprová
Publikováno v:
Pediatric research. 85(6)
The action spectrum for bilirubin photodegradation has been intensively studied. However, questions still remain regarding which light wavelength most efficiently photodegrades bilirubin. In this study, we determined the in vitro effects of different
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 161, p 161 (2021)
Pharmaceutics, Vol 13, Iss 161, p 161 (2021)
The increasing prevalence of colonic diseases calls for a better understanding of the various colonic drug absorption barriers of colon-targeted formulations, and for reliable in vitro tools that accurately predict local drug disposition. In vivo rel
Autor:
Farzaneh Ghazavi, Linyan Huang, Pedro Henrique Viana Saavedra, Tom Vanden Berghe, Peter Vandenabeele, Mohamed Lamkanfi, Stephanie Kourula, Nozomi Takahashi
Publikováno v:
NATURE COMMUNICATIONS
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature communications
Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this inflammatory condition via a cytotoxic response on intestinal epithelial cells (IECs), but the under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443e028d20e929aeaabf1a5f62fb8e6a
https://hdl.handle.net/1854/LU-8599172
https://hdl.handle.net/1854/LU-8599172
Autor:
David K. Stevenson, Stephanie Kourula, Joyce Ang, Flora Kalish, Peter Vandenabeele, Hui Zhao, Karl G. Sylvester, Ronald J. Wong
Publikováno v:
Neonatology. 112(4)
Background: Severe hemolytic disease of the newborn leads to the release of pro-oxidative free heme (FH). Heme oxygenase (HO) is primarily responsible for detoxifying FH. Objective: To investigate the protective effects of HO in a model of heme overl
Autor:
Lucie Muchová, Stephanie Kourula, Lucie Ludvíková, Hendrik J. Vreman, Jana Jašprová, Petr Klán, Benjamin K. Cline, David K. Stevenson, Ronald J. Wong, Libor Vítek
Publikováno v:
Pediatric Research. 85:905-905
Following publication of this article, the authors noticed that an incorrect affiliation was assigned to the author “Lucie Muchova”. The original article has now been updated so that the author “Lucie Muchova” is associated with the “Instit