Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stephanie K Lathrop"'
Autor:
Stephanie K. Lathrop, Jordan J. Clark, Karthik Siram, Robert Andreata-Santos, Jeremy Yong, Rebekah D. Tee, Clara J. Davison, Gagandeep Singh, David Burkhart, Florian Krammer, Jay T. Evans
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-12 (2024)
Abstract Many different platforms have been used to develop highly protective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans. However, protection has eroded over time due to the emergence of antigenically dive
Externí odkaz:
https://doaj.org/article/691de1013f4746969e948200a1fa7aec
Autor:
Karthik Siram, Stephanie K. Lathrop, Walid M. Abdelwahab, Rebekah Tee, Clara J. Davison, Haley A. Partlow, Jay T. Evans, David J. Burkhart
Publikováno v:
Vaccines, Vol 12, Iss 1, p 21 (2023)
Despite the availability of effective vaccines against COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread worldwide, pressing the need for new vaccines with improved breadth and durability. We developed an adju
Externí odkaz:
https://doaj.org/article/5588703beb6d4da48c23ab455bcdd91b
Autor:
Kristopher K. Short, Stephanie K. Lathrop, Clara J. Davison, Haley A. Partlow, Johnathan A. Kaiser, Rebekah D. Tee, Elizabeth B. Lorentz, Jay T. Evans, David J. Burkhart
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1455 (2022)
A diversity of vaccines is necessary to reduce the mortality and morbidity of SARS-CoV-2. Vaccines must be efficacious, easy to manufacture, and stable within the existing cold chain to improve their availability around the world. Recombinant protein
Externí odkaz:
https://doaj.org/article/dc040770076e4fe8bccc69c38335ffb0
Autor:
Stephanie K Lathrop, Hardik H Amin, Clara J Davison, Haley A Partlow, Elizabeth K Lorentz, David J Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 208:65.32-65.32
Subunit vaccines require an adjuvant, as protein antigens alone provoke a very poor immune response. Liposomes can be used to deliver an adjuvant, particularly when it is an amphipathic molecule such as a toll-like receptor (TLR) 4 agonist. TLR4 enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2258e488506d4afe6b777e0a0da85f0f
https://doi.org/10.4049/jimmunol.208.supp.65.32
https://doi.org/10.4049/jimmunol.208.supp.65.32
Autor:
Stephanie K Lathrop, Casey J. Massena, Clara J. Davison, Roman Schoener, David J. Burkhart, Jay T. Evans
Publikováno v:
The Journal of Immunology. 206:102.09-102.09
When designing an effective and safe vaccine, the induction of a protective immune response to a pathogen without unacceptable levels of immunopathology is critical. The use of purified or recombinant antigens in combination with adjuvants that elici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741adbdf19359726e433054f98b36625
https://doi.org/10.4049/jimmunol.206.supp.102.09
https://doi.org/10.4049/jimmunol.206.supp.102.09
Publikováno v:
The Journal of Immunology. 206:30.06-30.06
Adjuvanted subunit vaccines offer improved safety and efficacy over whole inactivated or live attenuated vaccines by incorporating recombinant proteins with highly selective innate immune activators. Selection of an antigen in subunit vaccines can al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d64ca74c6fab15db26f07c146b0a8d6a
https://doi.org/10.4049/jimmunol.206.supp.30.06
https://doi.org/10.4049/jimmunol.206.supp.30.06
Autor:
Shelby L Cole, Van A Cybulski, Margaret Whitacre, Stephanie K Lathrop, Helene Bazin-Lee, David Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 204:245.12-245.12
Influenza virus infection is a global health concern and causes severe illness and thousands of deaths each year. While there are currently licensed vaccines available for both seasonal and pandemic influenza viruses there are several issues to consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::567020f77ab638a7af5266763ea2e842
https://doi.org/10.4049/jimmunol.204.supp.245.12
https://doi.org/10.4049/jimmunol.204.supp.245.12
Autor:
Stephanie K Lathrop, Casey J Massena, Clara J Davison, Roman Schoener, David J Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 204:245.8-245.8
When designing an effective and safe vaccine, inducing a protective immune response to a pathogen without also inducing unacceptable levels of immunopathology is a major challenge. One promising strategy is the use of purified or recombinant antigens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc34519316ea2cb2cc3a23991a740c8
https://doi.org/10.4049/jimmunol.204.supp.245.8
https://doi.org/10.4049/jimmunol.204.supp.245.8
Autor:
Aaron B. Carmody, Olivia Steele-Mortimer, Kelsey A. Binder, Kendal G. Cooper, Audrey Chong, Stephanie K. Lathrop, Tregei Starr
Publikováno v:
Infection and Immunity. 83:2661-2671
Salmonella enterica serovar Typhimurium is a common cause of food-borne gastrointestinal illness, but additionally it causes potentially fatal bacteremia in some immunocompromised patients. In mice, systemic spread and replication of the bacteria dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633df404b0e3e4c26aff1192846500b9
https://doi.org/10.1128/iai.00033-15
https://doi.org/10.1128/iai.00033-15
Autor:
Sindhuja Rao, Nicole A. Santacruz, Stephanie K. Lathrop, Katherine Nutsch, Thaddeus S. Stappenbeck, Chyi-Song Hsieh, Seth M. Bloom, Daniel A. Peterson, Chan-Wang J. Lio
Publikováno v:
Nature
Understanding how the immune system becomes tolerant to foreign antigens from commensal bacteria is a fundamental question, as breakdown of tolerance can result in unwanted responses such as inflammatory bowel disease. It has been suggested that tole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c939b975f5581ec656573ecd7205abe
https://doi.org/10.1038/nature10434
https://doi.org/10.1038/nature10434