Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephanie Joaquim"'
Autor:
Ja Young Kim-Muller, LouJin Song, Brianna LaCarubba Paulhus, Evanthia Pashos, Xiangping Li, Anthony Rinaldi, Stephanie Joaquim, John C. Stansfield, Jiangwei Zhang, Andrew Robertson, Jincheng Pang, Alan Opsahl, Magalie Boucher, Danna Breen, Katherine Hales, Abdul Sheikh, Zhidan Wu, Bei B. Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111947- (2023)
Summary: Cancer cachexia is a disorder characterized by involuntary weight loss and impaired physical performance. Decline in physical performance of patients with cachexia is associated with poor quality of life, and currently there are no effective
Externí odkaz:
https://doaj.org/article/7269fc75244043ad853bd7fb8484fed2
Autor:
Danna M. Breen, Srinath Jagarlapudi, Anita Patel, Chang Zou, Stephanie Joaquim, Xiangping Li, Liya Kang, Jincheng Pang, Katherine Hales, Enida Ziso-Qejvanaj, Nicholas B. Vera, Donald Bennett, Tao He, Matthew Lambert, Kerry Kelleher, Zhidan Wu, Bei B. Zhang, Laura Lin, Randy J. Seeley, Olivier Bezy
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102554- (2021)
Summary: Growth differentiation factor 15 (GDF15) causes anorexia and weight loss in animal models, and higher circulating levels are associated with cachexia and reduced survival in cancer and other chronic diseases such as sepsis. To investigate th
Externí odkaz:
https://doaj.org/article/8328784525fa4ccbba52dec8758e63fb
Autor:
Kent E Pedersen, Hanna Kim, Anthony J. Rostron, Samuel M. Lockhart, Y. C. Loraine Tung, Stephanie Joaquim, Keith Burling, A. John Simpson, Sebastian Beck Jørgensen, Giles Sh Yeo, E-Chiang Lee, Audrey Melvin, Danna M. Breen, Menna R. Clatworthy, Irene Cimino, Kendra K. Bence, Debra Rimmington, Stephen O'Rahilly, Peter Barker, Jonathan M. Scott, André Barros, Ana Neves-Costa, John Tadross, Anthony P. Coll, Luis F. Moita, Hui Liu, Don Bennett, Sara Kohnke
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance GDF15, a hormone produced by a wide variety of cells undergoing different types of stress, acts on a receptor in the brain where it transmits signals that are perceived by the organism as aversive. We now report an action of GDF15, where
Autor:
Kerry Kelleher, Olivier Bezy, Laura Lin, Xiangping Li, Srinath Jagarlapudi, Danna M. Breen, Enida Ziso-Qejvanaj, Bei B. Zhang, Jincheng Pang, Donald Bennett, Chang Zou, Liya Kang, Stephanie Joaquim, Zhidan Wu, Nicholas B. Vera, Anita Patel, Matthew Allister Lambert, Katherine Hales, Tao He, Randy J. Seeley
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102554-(2021)
iScience
iScience
Summary Growth differentiation factor 15 (GDF15) causes anorexia and weight loss in animal models, and higher circulating levels are associated with cachexia and reduced survival in cancer and other chronic diseases such as sepsis. To investigate the
Autor:
Jeonifer Garren, Hanna Kim, Shuxi Qiao, Matthew Peloquin, Magalie Boucher, Zhidan Wu, Danna M. Breen, Ryan M. Esquejo, Stephanie Joaquim, Brianna LaCarubba, Barbara Bernardo, Christopher Houle
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Background Cancer cachexia is a complex metabolic disease with unmet medical need. Although many rodent models are available, none are identical to the human disease. Therefore, the development of new preclinical models that simulate some of the phys
Autor:
Morris J. Birnbaum, Matthew Allister Lambert, Betty Pettersen, Donald Bennett, Michelle Rossulek, Gregory Weber, Shuxi Qiao, Ryan M. Esquejo, Tao He, Roberto A. Calle, Bei B. Zhang, Laura Lin, Zhidan Wu, Danna M. Breen, Susie Collins, Hanna Kim, Alison Joyce, Stephanie Joaquim
Publikováno v:
Cell Metabolism. 32:938-950.e6
Platinum-based cancer therapy is restricted by dose-limiting side effects and is associated with elevation of growth differentiation factor 15 (GDF-15). But whether this elevation contributes to such side effects has been unclear. Here, we explored t
Autor:
Roberto A. Calle, J.Y. Kim-Muller, Laura Lin, Danna M. Breen, Morris J. Birnbaum, Gregory Weber, Zhidan Wu, Michelle Rossulek, Brianna LaCarubba, Ryan M. Esquejo, Julia Brosnan, Hanna Kim, Susie Collins, Alison Joyce, Stephanie Joaquim, Shuxi Qiao, Matthew Peloquin, Bei Betty Zhang, Betty Pettersen, Donald Bennett
Publikováno v:
Annals of Oncology. 31:S245
Autor:
Roberto A. Calle, Danna M. Breen, Susie Collins, Hanna Kim, Shuxi Qiao, Alison Joyce, Bei B. Zhang, Kevin Beaumont, Michelle Rossulek, Laura Lin, Julia Brosnan, Brendan Tierney, Morris J. Birnbaum, Betty Pettersen, Donald Bennett, Zhidan Wu, Ryan M. Esquejo, Gregory Weber, Karen Walters, Stephanie Joaquim, Teresa Cunio, Jeffrey R. Chabot
Publikováno v:
Cancer Research. 80:3056-3056
Platinum-based chemotherapy is associated with nausea/emesis, anorexia and weight loss which reduce patient quality of life and limit treatment adherence potentially leading to poor treatment outcomes. Cisplatin increases circulating growth different
Autor:
Srinath Jagarlapudi, Zhidan Wu, Olivier Bezy, Chang Zou, Danna M. Breen, Randy J. Seeley, Bei Betty Zhang, Donald Bennett, Anita Patel, Stephanie Joaquim
Publikováno v:
Journal of Clinical Oncology. 38:e24153-e24153
e24153 Background: Growth differentiation factor 15 (GDF-15) is a cytokine that induces anorexia, weight loss and has been reported to be associated with cachexia and poor survival in illnesses characterized by inflammation such as cancer cachexia an