Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephanie Jean Wallace"'
Publikováno v:
Journal of Pharmaceutical Sciences. 101:3347-3359
Interaction of colistin and colistin methanesulfonate (CMS) with liposomes has been studied with the view to understanding the limitations to the use of liposomes as a more effective delivery system for pulmonary inhalation of this important class of
Autor:
Richard John Prankerd, Roger L. Nation, Jian Li, Tony Velkov, Stephanie Jean Wallace, Benjamin James Boyd
Publikováno v:
The Journal of Physical Chemistry B. 114:4836-4840
Colistin is an amphiphilic antibiotic that has re-emerged into clinical use due to the increasing prevalence of difficult-to-treat Gram-negative infections. The existence of self-assembling colloids in solutions of colistin and its derivative prodrug
Publikováno v:
Antimicrobial Agents and Chemotherapy. 52:3047-3051
Colistin methanesulfonate (CMS) has the potential to hydrolyze in aqueous solution to liberate colistin, its microbiologically active and more toxic parent compound. While conversion of CMS to colistin in vivo is important for bactericidal activity,
Publikováno v:
Journal of pharmaceutical sciences. 102(5)
Remote loading of azithromycin into liposomes, and subsequent release behavior in the presence of colistin, has been investigated with a view to understand the potential of liposomes to enable the coformulation of these two antibiotics for applicatio
Publikováno v:
Drug delivery and translational research. 2(4)
The characterization of encapsulation efficiency and in vitro drug release from nanoparticle-based formulations often requires the separation of nanoparticles from unencapsulated drug. Inefficient separation of nanoparticles from the medium in which
Autor:
Kingsley Coulthard, John D. Turnidge, Craig R Rayner, Roger L. Nation, Robert W. Milne, Deborah Middleton, Jian Li, Stephanie Jean Wallace, David Taylor
The relative nephro- and neurotoxicity of colistin methanesulfonate (CMS) was investigated with rats during 7 days of intravenous administration in regimens mimicking twice- and once-daily dosing of a clinically relevant dose for humans. Histological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eebcfa1ec032943a910f3551fb1c1db
https://hdl.handle.net/11541.2/112711
https://hdl.handle.net/11541.2/112711