Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie J. Soscia"'
Autor:
Jorge F. Haller, Paul Cavallaro, Nicholas J. Hernandez, Lee Dolat, Stephanie J. Soscia, Ruth Welti, Gregory A. Grabowski, Michael L. Fitzgerald, Mason W. Freeman
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 3, Pp 493-503 (2014)
ABCA12 mutations disrupt the skin barrier and cause harlequin ichthyosis. We previously showed Abca12−/− skin has increased glucosylceramide (GlcCer) and correspondingly lower amounts of ceramide (Cer). To examine why loss of ABCA12 leads to accu
Externí odkaz:
https://doaj.org/article/61096b968579476984c13ed742b53d1c
Autor:
Juliet A Moncaster, Roberto Pineda, Robert D Moir, Suqian Lu, Mark A Burton, Joy G Ghosh, Maria Ericsson, Stephanie J Soscia, Anca Mocofanescu, Rebecca D Folkerth, Richard M Robb, Jer R Kuszak, John I Clark, Rudolph E Tanzi, David G Hunter, Lee E Goldstein
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10659 (2010)
Down syndrome (DS, trisomy 21) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans. In DS, triplication of chromosome 21 invariably includes the APP gene (21q21) encoding the Alzheimer's disease
Externí odkaz:
https://doaj.org/article/68140f0c02854f30afc460197196eda9
Autor:
Stephanie J Soscia, James E Kirby, Kevin J Washicosky, Stephanie M Tucker, Martin Ingelsson, Bradley Hyman, Mark A Burton, Lee E Goldstein, Scott Duong, Rudolph E Tanzi, Robert D Moir
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9505 (2010)
The amyloid beta-protein (Abeta) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Abeta is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. However, Abeta has been shown to
Externí odkaz:
https://doaj.org/article/42b9b2344e1f41cbb83e8af082698963
Publikováno v:
Clinical Lipidology. 8:97-108
ABCA7 is part of the ABCA superfamily of cholesterol and phospholipid transporters that move lipids and other molecules across membranes. The ABCA7 locus was one of four loci implicated in Alzheimer’s disease (AD) susceptibility in a recent genome-
Autor:
Stephanie J. Soscia, Cheruba Prabakar, Mary E. Harrington, Penny C. Molyneux, Judy McKinley-Brewer, Gurprit S. Lall
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 292:R1306-R1314
The cycle length or period of the free-running rhythm is a key characteristic of circadian rhythms. In this study we verify prior reports that locomotor activity patterns and running wheel access can alter the circadian period, and we report that the
Publikováno v:
Neuroscience Letters. 373:175-178
Mammalian circadian rhythms are modulated by neuropeptide Y (NPY), a peptide contained in the projection from the intergeniculate leaflet to the suprachiasmatic nuclei of the circadian pacemaker. NPY resets the circadian clock during the subjective d
Autor:
Nicholas J. Hernandez, Michael L. Fitzgerald, Lee Dolat, Ruth Welti, Paul M Cavallaro, Gregory A. Grabowski, Mason W. Freeman, Jorge F. Haller, Stephanie J. Soscia
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 3, Pp 493-503 (2014)
ABCA12 mutations disrupt the skin barrier and cause harlequin ichthyosis. We previously showed Abca12(-/-) skin has increased glucosylceramide (GlcCer) and correspondingly lower amounts of ceramide (Cer). To examine why loss of ABCA12 leads to accumu
Autor:
Rudolph E. Tanzi, Stephanie J. Soscia, Suqian Lu, Rebecca D. Folkerth, Joy Ghosh, Anca Mocofanescu, Jer R. Kuszak, Maria Ericsson, Richard M. Robb, Roberto Pineda, Juliet A. Moncaster, David G. Hunter, Mark Burton, Robert D. Moir, John I. Clark, Lee E. Goldstein
Publikováno v:
Alzheimer's & Dementia. 6
Down syndrome (DS, trisomy 21) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans. In DS, triplication of chromosome 21 invariably includes the APP gene (21q21) encoding the Alzheimer's disease
Autor:
Mark Burton, Rudolph E. Tanzi, Robert D. Moir, Bradley T. Hyman, James E. Kirby, Lee E. Goldstein, Stephanie Tucker, Martin Ingelsson, Kevin J. Washicosky, Scott Duong, Stephanie J. Soscia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 3, p e9505 (2010)
PLoS ONE, Vol 5, Iss 3, p e9505 (2010)
Background The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. However, Aβ has been shown
Publikováno v:
Alzheimer's & Dementia. 4