Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephanie J. Lent"'
Publikováno v:
Journal of the American Geriatrics Society. 54:980-985
Autor:
Steven Barczi, Stephanie J. Lent, Molly Carnes, Lisa L. Boyle, William B. Ershler, Adalsteinn Gudmundsson, Ana Grace, Brian Goodman
Publikováno v:
Experimental Gerontology. 34:809-818
Estrogen replacement therapy (ERT) seems to enhance longevity in women. Both gender and aging have been shown to influence the regulation of circadian rhythms, yet little is known about the effect of ERT on circadian regulation. The aim of this study
Publikováno v:
Life Sciences. 54:1659-1669
Using high intensity venous sampling (1-2 min integrated intervals) we have observed rapid (< 10 min) large amplitude (up to 80 pg/ml) fluctuations in plasma ACTH concentrations in addition to variations at longer time scales. We developed a mathemat
Publikováno v:
Endocrinology. 133:608-616
Dysregulation of the hypothalamic-pituitary-adrenocortical axis has been theoretically linked to the processes of aging for decades. To investigate the effects of age on high frequency rhythms of plasma ACTH at the time of circadian activation, integ
Autor:
Peter A. Rittenhouse, Cynthia L. Bethea, Stephanie J. Lent, Mark S. Brownfield, Louis D. Van de Kar, Molly Carnes, Thomas Palionis, Patricia A. O'Connor
Publikováno v:
Biological Psychiatry. 32:258-269
This study was undertaken to examine whether several of the hormones that can be released by activation of serotonin receptors will be affected by long-term cocaine administration. Male rats received cocaine injections (15 mg/kg, IP) twice daily for
Autor:
L.D. Van de Kar, Janice E. Kerr, Lalitha Iyer, Maria C. Alvarez Sanz, Molly Carnes, Peter A. Rittenhouse, Stephanie J. Lent, Anna M. Bonadonna, G.B. Herbert, Andrew D. Levy
Publikováno v:
Neuropharmacology. 31:169-175
The effect of long-term pretreatment with cocaine on serotonergic regulation of ACTH (adrenocorticotropic hormone; corticotropin) and secretion of corticosterone in rats was investigated. The following observations were made: (1) Pretreatment with co
Publikováno v:
Neuroendocrinology. 55:97-104
Insulin-induced hypoglycemia is a metabolic stress that stimulates secretion of adrenocorticotropic hormone (ACTH) and cortisol in a number of animal species. Dexamethasone is a potent synthetic glucocorticoid that suppresses the secretion of ACTH an
Publikováno v:
Endocrinology. 128:902-910
Time series of plasma ACTH concentrations were analyzed with a high resolution spectral analysis program based on digital Fourier transforms. Both coherent signal and stochastic aspects of the time series were analyzed. Samples were collected at 2- a
Autor:
Stephanie J. Lent, Susan Erisman, Joel Saydoff, Molly Carnes, Christopher R. Mueller, Brian Goodman
Publikováno v:
Endocrinology. 126:1904-1913
ACTH, like other anterior pituitary peptide hormones, is secreted episodically and demonstrates both circadian and ultradian rhythms. CRH is the major regulator of ACTH release from the pituitary corticotroph. To determine the dependence of ACTH ultr
Publikováno v:
Life Sciences. 47:1527-1533
Compared to younger rats, old rats exhibit prolonged elevations of plasma ACTH and corticosterone (CORT) in response to stress. In addition, CORT crosses the placenta. To investigate whether fetuses of older rats may be exposed to higher concentratio