Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Stephanie J. Gros"'
Autor:
Stefanie Volkart, Urs Kym, Olivier Braissant, Edgar Delgado-Eckert, Samer Al-Samir, Rebecca Angresius, Zihe Huo, Stefan Holland-Cunz, Stephanie J. Gros
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3616 (2023)
Aquaporin 1 (AQP1) is one of thirteen known mammalian aquaporins. Its main function is the transport of water across cell membranes. Lately, a role of AQP has been attributed to other physiological and pathological functions including cell migration
Externí odkaz:
https://doaj.org/article/6aa097cfd042426188c0b6d036452092
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The water channel aquaporin 1 (AQP1) has been implicated in tumor progression and metastasis. It is hypothesized that AQP1 expression can facilitate the transmembrane water transport leading to changes in cell structure that promote migration. Its im
Externí odkaz:
https://doaj.org/article/90b726667226422f8de9c1b0c15aa286
Autor:
Zihe Huo, Remo Bilang, Claudiu T. Supuran, Nicolas von der Weid, Elisabeth Bruder, Stefan Holland-Cunz, Ivan Martin, Manuele G. Muraro, Stephanie J. Gros
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3128 (2022)
Neuroblastoma is a rare disease. Rare are also the possibilities to test new therapeutic options for neuroblastoma in clinical trials. Despite the constant need to improve therapy and outcomes for patients with advanced neuroblastoma, clinical trials
Externí odkaz:
https://doaj.org/article/a1aeca704acd4392ab31b935fff1cbf5
Autor:
Astrid Drenckhan, Morton Freytag, Claudiu T. Supuran, Guido Sauter, Jakob R. Izbicki, Stephanie J. Gros
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1024-1033 (2018)
The hypoxic tumour microenvironment of solid tumours represents an important starting point for modulating progression and metastatic spread. Carbonic anhydrase IX (CAIX) is a known HIF-1α-dependent key player in maintaining cell pH conditions under
Externí odkaz:
https://doaj.org/article/f578c1902d0f4b5585eae8497dea9bcf
Publikováno v:
Children, Vol 8, Iss 9, p 784 (2021)
Neuroblastoma, like other cancer types, has an increased need for energy. This results in an increased thermogenic profile of the cells. How tumor cells optimize their energy efficiency has been discussed since Warburg described the fact that tumor c
Externí odkaz:
https://doaj.org/article/74ea9ecfd9e34abba08c07152fddaf75
Autor:
Nora Manz, Claudia Höfele-Behrendt, Julia Bielicki, Hanna Schmid, Matthias S. Matter, Isabella Bielicki, Stefan Holland-Cunz, Stephanie J. Gros
Publikováno v:
Children, Vol 8, Iss 8, p 712 (2021)
Background: multisystem inflammatory syndrome in children (MIS-C) is a new disease associated with a recent infection with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). Affected children can present predominantly with abdominal s
Externí odkaz:
https://doaj.org/article/16f7063ca864423c98f014cec00ba9f0
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 25, Iss C, Pp 52-55 (2017)
Introduction: Necrotizing fasciitis is a soft tissue infection that can rapidly progress and end lethally if not treated early and radically. With an extremely low prevalence (0.02% of all pediatric in hospital cases), most physicians will probably o
Externí odkaz:
https://doaj.org/article/8163708ef45c4235b249052441c876af
Autor:
Nicola Pini, Viktoria A. Pfeifle, Urs Kym, Simone Keck, Virginie Galati, Stefan Holland-Cunz, Stephanie J. Gros
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1036-1041 (2017)
Acute appendicitis is the most common indication for pediatric abdominal emergency surgery. Determination of the severity of appendicitis on clinical grounds is challenging. Complicated appendicitis presenting with perforation, abscess or diffuse per
Externí odkaz:
https://doaj.org/article/dac2e616b06442b2a4c128f6c48259d2
Autor:
Zihe Huo, Mariana Sá Santos, Astrid Drenckhan, Stefan Holland-Cunz, Jakob R. Izbicki, Michael A. Nash, Stephanie J. Gros
Publikováno v:
Cells, Vol 10, Iss 5, p 1213 (2021)
Despite continuous improvements in multimodal therapeutic strategies, esophageal carcinoma maintains a high mortality rate. Metastases are a major life-limiting component; however, very little is known about why some tumors have high metastatic poten
Externí odkaz:
https://doaj.org/article/fc923052592b46f78bac3f21419265e8
Autor:
Alexander Kapp, David Troxler, Friederike Prüfer, Stefan Holland-Cunz, Martina Frech, Stephanie J. Gros
Publikováno v:
Children, Vol 8, Iss 6, p 429 (2021)
Testicular torsion is a surgical emergency. Early diagnosis and surgical treatment are vital in order to preserve the affected gonad. Current surgical teaching emphasizes sudden, severe, persistent, unilateral scrotal pain as a cardinal symptom of te
Externí odkaz:
https://doaj.org/article/4753332b619744c2aa481885cce37dc8