Výsledky vyhledávání - "Stephanie J. Garland"

Akademický článek

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT).

Autor: Tiffany A Timbers, Stephanie J Garland, Swetha Mohan, Stephane Flibotte, Mark Edgley, Quintin Muncaster, Vinci Au, Erica Li-Leger, Federico I Rosell, Jerry Cai, Suzanne Rademakers, Gert Jansen, Donald G Moerman, Michel R Leroux

Publikováno v: PLoS Genetics, Vol 12, Iss 8, p e1006235 (2016)

Forward genetic screens represent powerful, unbiased approaches to uncover novel components in any biological process. Such screens suffer from a major bottleneck, however, namely the cloning of corresponding genes causing the phenotypic variation. R

Externí odkaz: https://doaj.org/article/92ee75ab091a429ab63000dd1b802093

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Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT)

Autor: Stephane Flibotte, Federico I. Rosell, Mark L. Edgley, Erica Li-Leger, Swetha Mohan, Suzanne Rademakers, Jerry Cai, Donald G. Moerman, Michel R. Leroux, Quintin Muncaster, Tiffany A. Timbers, Vinci Au, Gert Jansen, Stephanie J. Garland

Publikováno v: PLoS Genetics (online), 12(8). Public Library of Science
PLoS Genetics, Vol 12, Iss 8, p e1006235 (2016)
PLoS Genetics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2723c0546ec4a08cc72b5c530d2b5db
https://doi.org/10.1371/journal.pgen.1006235

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Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity

Autor: Marie Gestin, Neal D. Mathew, Mark D. Mathew, Stephanie J. Garland, Mark L. Edgley, Pamela Dean, Guri Giaever, Stephane Flibotte, Jennifer Chiang, Calvin D. Roskelley, Audrey Tung, Aruna D. Balgi, Angela Miller, Tom Forge, Vinci Au, Corey Nislow, Michael G. Simpson, Michel Roberge, Donald G. Moerman

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005058 (2016)

Background The lack of new anthelmintic agents is of growing concern because it affects human health and our food supply, as both livestock and plants are affected. Two principal factors contribute to this problem. First, nematode resistance to anthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e9b56ad1bdfdbd3f745591670edbd5
https://doi.org/10.1371/journal.pntd.0005058

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