Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephanie J. Culler"'
Autor:
Henry Man, Gideon Grogan, Stephen J. Van Dien, Rosary Stephen, Christopher Geinitz, Stephanie J. Culler, Robert Haselbeck, Stephanie J. Popa, Bernhard Hauer, Muhiadin Omar, Johan P. Turkenburg, Erik C Ralph, Max-Philipp Fischer, Hoi Ting Hau, Bettina M. Nestl, Sari Rizek, Michael A Noble
Publikováno v:
Nature Chemical Biology
The asymmetric dehydration of alcohols is an important process for the direct synthesis of alkenes. We report the structure and substrate specificity of the bifunctional linalool dehydratase isomerase (LinD) from the bacterium Castellaniella defragra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e45c2b8531c7038f78605d9e49366a4
https://doi.org/10.1038/nchembio.2271
https://doi.org/10.1038/nchembio.2271
Autor:
Harish Nagarajan, Hirokazu Sato, Hongjun Huang, Tae Hoon Yang, Stephen J. Van Dien, Richard M. Murray, Julia Khandurina, Yong Y. Wu, Stephanie J. Culler
Current methods for assembling biosynthetic pathways in microorganisms require a process of repeated trial and error and have long design-build-test cycles. We describe the use of a cell-free transcription-translation (TX-TL) system as a biomolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5479e787c447b44da7b004599168a376
https://doi.org/10.1101/172007
https://doi.org/10.1101/172007
Publikováno v:
Science. 330:1251-1255
Cellular Devices Cellular control mechanisms might offer opportunities to build genetic devices capable of sensing aberrant cells and activate a regulatory signal that directs the cell to alter its biological state. Culler et al. (p. 1251 ; see the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45f7d9a0a0601a4f3b71463dae6fca5
https://doi.org/10.1126/science.1192128
https://doi.org/10.1126/science.1192128
Current methods for assembling metabolic pathways require a process of repeated trial and error and have a long design-build-test cycle. Further, it remains a challenge to precisely tune enzyme expression levels for maximizing target metabolite produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7a06b501f1a04fa1e7167269e22d56
https://doi.org/10.1101/017814
https://doi.org/10.1101/017814
Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing
Publikováno v:
Nucleic acids research, vol 39, iss 7
Nucleic Acids Research
Nucleic Acids Research
MicroRNAs (miRNAs) are prevalent regulatory RNAs that mediate gene silencing and play key roles in diverse cellular processes. While synthetic RNA-based regulatory systems that integrate regulatory and sensing functions have been demonstrated, the la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab6ec3e16dc28a9fb41b773027e5abc
https://escholarship.org/uc/item/2jv8m1tn
https://escholarship.org/uc/item/2jv8m1tn
Autor:
J. Andrew Berglund, Rodger B. Voelker, Stephanie J. Culler, Kevin G. Hoff, Christina D. Smolke
Publikováno v:
Nucleic Acids Research
Despite the critical role of pre-mRNA splicing in generating proteomic diversity and regulating gene expression, the sequence composition and function of intronic splicing regulatory elements (ISREs) have not been well elucidated. Here, we employed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4684e4a5c5b42c39e79c1c41a006699
https://pubmed.ncbi.nlm.nih.gov/20385591
https://pubmed.ncbi.nlm.nih.gov/20385591
Autor:
Kevin G. Hoff, Stephanie J. Culler, Ryan M. McGuire, Jonathan J. Silberg, Christina D. Smolke, Peter Q. Nguyen
Publikováno v:
Chemistrybiology. 16(12)
SummaryA major challenge to studying Fe-S cluster biosynthesis in higher eukaryotes is the lack of simple tools for imaging metallocluster binding to proteins. We describe the first fluorescent approach for in vivo detection of 2Fe2S clusters that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b972aaa5fea69fe100568cdbb86c85
https://pubmed.ncbi.nlm.nih.gov/20064428
https://pubmed.ncbi.nlm.nih.gov/20064428