Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stephanie J. B. Fretham"'
Autor:
Li-Lian Yuan, Robert J. Wickham, Jianjun Su, Michael K. Georgieff, Stephanie J. B. Fretham, Marc T. Pisansky, Jonathan C. Gewirtz, Mu Sun
Publikováno v:
Hippocampus. 23:952-962
Iron deficiency (ID) during early life causes long-lasting detrimental cognitive sequelae, many of which are linked to alterations in hippocampus function, dopamine synthesis, and the modulation of dopaminergic circuitry by the hippocampus. These sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14b571c866ba665e0d40cda0611a8357
https://doi.org/10.1002/hipo.22151
https://doi.org/10.1002/hipo.22151
Publikováno v:
Toxicology Research. 1:32-38
The neurotoxic consequences of methylmercury (MeHg) exposure have long been known, however a complete understanding of the mechanisms underlying this toxicity is elusive. Recent epidemiological and experimental studies have provided mechanistic insig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4630067513ec25f92bf5521b72aded1d
https://doi.org/10.1039/c2tx20010d
https://doi.org/10.1039/c2tx20010d
Autor:
Erik S. Carlson, Anna Petryk, Phu V. Tran, Michael K. Georgieff, Stephanie J. B. Fretham, Jane D. Wobken
Publikováno v:
Hippocampus. 22:1691-1702
Iron is a necessary substrate for neuronal function throughout the lifespan, but particularly during development. Early life iron deficiency (ID) in humans (late gestation through 2–3 years) results in persistent cognitive and behavioral abnormalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c4a85cbd027c56eff8ee4144ca4202
https://doi.org/10.1002/hipo.22004
https://doi.org/10.1002/hipo.22004
Autor:
Jane D. Wobken, Stephanie J. B. Fretham, Phu V. Tran, Bradley S. Miller, Michael K. Georgieff
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 302:E316-E324
Gestational-neonatal iron deficiency, a common micronutrient deficiency affecting the offspring of more than 30% of pregnancies worldwide, leads to long-term cognitive and behavioral abnormalities. Preclinical models of gestational-neonatal iron defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd030ac466a01d7a456a1452eb755304
https://doi.org/10.1152/ajpendo.00369.2011
https://doi.org/10.1152/ajpendo.00369.2011
Publikováno v:
Advances in Nutrition. 2:112-121
Iron deficiency (ID) is the most common nutrient deficiency, affecting 2 billion people and 30% of pregnant women and their offspring. Early life ID affects at least 3 major neurobehavioral domains, including speed of processing, affect, and learning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320364a1f661b4e29bd247d195d1effc
https://doi.org/10.3945/an.110.000190
https://doi.org/10.3945/an.110.000190
Publikováno v:
Pediatric Research. 65:493-498
Fetal-neonatal iron deficiency acutely alters hippocampal biochemistry, neural morphology, and electrophysiology accompanied by a downregulation of brain-derived neurotrophic factor (BDNF). These changes provide a cellular and molecular basis for obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0279a736e85edea1dd8d0163ac368bd5
https://doi.org/10.1203/pdr.0b013e31819d90a1
https://doi.org/10.1203/pdr.0b013e31819d90a1
Publikováno v:
The Journal of Nutrition. 138:2495-2501
Fetal-neonatal iron deficiency alters hippocampal neuronal morphology, reduces its volume, and is associated with acute and long-term learning impairments. However, neither the effects of early-life iron deficiency anemia on growth, differentiation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33cbb6b99befd37eb5b19d80a38372e
https://doi.org/10.3945/jn.108.091553
https://doi.org/10.3945/jn.108.091553
Publikováno v:
Binding, Transport and Storage of Metal Ions in Biological Cells ISBN: 9781849735995
Mercury (Hg) is a non-essential, naturally occurring metal with many industrial uses. Most forms of Hg are highly toxic to both prokaryotic and eukaryotic organisms. There are no known biological proteins or processes that require Hg; however, unlike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e070a77c9f0ff71dd6cae0c7d7a2c89
https://doi.org/10.1039/9781849739979-00747
https://doi.org/10.1039/9781849739979-00747
Autor:
Grant W. Anderson, Joseph R. Prohaska, Thomas W. Bastian, Jeremy A. Anderson, Michael K. Georgieff, Stephanie J. B. Fretham
Publikováno v:
Endocrinology. 153(11)
Copper (Cu), iron (Fe), and thyroid hormone (TH) deficiencies produce similar defects in late brain development including hypomyelination of axons and impaired synapse formation and function, suggesting that these micronutrient deficiencies share a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe03591483b90ee61b1b24e20ad6e77
https://pubmed.ncbi.nlm.nih.gov/23054056
https://pubmed.ncbi.nlm.nih.gov/23054056