Protein Mannosylation as a Diagnostic and Prognostic Biomarker of Lupus Nephritis: An Unusual Glycan Neoepitope in Systemic Lupus Erythematosus

Autor: Carlos Vasconcelos, Lèlita Santos, Hans Dalebout, Manfred Wuhrer, Ana Campar, Salomé S. Pinho, Ramon Vizcaíno, Inês Alves, Manuel M. Vicente, Franck Fieschi, Roberto Carlos Delmas da Silva, Beatriz Santos-Pereira, Sofia Santos, Stephanie Holst-Bernal, Fanny Boyaval, Bram Heijs, António Marinho, Michel Thépaut, Sabine Strahl

Publikováno v: Arthritis and Rheumatology. WILEY
Arthritis and Rheumatology
Arthritis & rheumatology
Arthritis & rheumatology, 2021, ⟨10.1002/art.41768⟩
Arthritis & rheumatology, Wiley, 2021, ⟨10.1002/art.41768⟩

Objectives Changes in protein glycosylation are a hallmark of immune-mediated diseases. Glycans are master regulators of the inflammatory response being important molecules for the discrimination between "self"/"non-self". We here explored whether lu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596e99aecb894b81bf4ba25aa1582964
https://doi.org/10.1002/art.41768

Molecular signatures of tumor progression in myxoid liposarcoma identified by N-glycan mass spectrometry imaging

Autor: Bram, Heijs, Stephanie, Holst-Bernal, Marieke A, de Graaff, Inge H, Briaire-de Bruijn, Mar, Rodriguez-Girondo, Michiel A J, van de Sande, Manfred, Wuhrer, Liam A, McDonnell, Judith V M G, Bovée

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 100(9)

Myxoid liposarcoma (MLS) is the second most common subtype of liposarcoma, accounting for ~6% of all sarcomas. MLS is characterized by a pathognomonic FUS-DDIT3, or rarely EWSR1-DDIT3, gene fusion. The presence of ≥5% hypercellular round cell areas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32a8ff9e5210494431a9975b0e4edf3e
https://pubmed.ncbi.nlm.nih.gov/32341520