Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephanie Goulet"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56015 (2013)
BACKGROUND: In allergic asthma, IgE increases airway remodelling but the mechanism is incompletely understood. Airway remodelling consists of two independent events increased cell numbers and enhanced extracellular matrix deposition, and the mechanis
Externí odkaz:
https://doaj.org/article/d213a94c31334da0af2f1541b7fc6a4e
Autor:
Katrin Hostettler, Janette K. Burgess, Stephanie Goulet, Michael Roth, Judith L. Black, Peter Borger, Michael Tamm, Jun Jun Zhong
Publikováno v:
The Open Critical Care Medicine Journal. 2:28-37
Rationale: Inflammation, increased fibroblast proliferation, and increased deposition of extracellular matrix (ECM) are hallmarks of early lung fibrosis and asthma. Transforming growth factor-� (TGF-� ) has been suggested as a key regulator of lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ded9df902c37d6742bdffe7cf7521a
https://doi.org/10.2174/1874828700902010028
https://doi.org/10.2174/1874828700902010028
Autor:
George Karakiulakis, Michael Roth, Judith L. Black, Eleni Papakonstantinou, Jun Zhong, Ioannis Klagas, Stephanie Goulet, Melissa Baraket
Publikováno v:
European Respiratory Journal. 34:616-628
Glycosaminoglycans (GAG) are essential extracellular matrix molecules which regulate tissue flexibility, a parameter that is reduced in airways of patients with asthma and chronic obstructive pulmonary disease (COPD). We investigated the expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a372ba3af3f60655b25bd28dcaf97891
https://doi.org/10.1183/09031936.00070808
https://doi.org/10.1183/09031936.00070808
Autor:
Stephanie Goulet, Michael Roth, Jochen J. Rüdiger, Michael Tamm, Jing-Qing Yang, J. Margaret Hughes, Pieter Borger, Mesut M. Gencay-Cornelson
Publikováno v:
American journal of respiratory cell and molecular biology
The glucocorticoid receptor (GR) is a major control factor for proliferation, differentiation, and inflammation. Our knowledge about the GR is focused on its function as a transcription regulator. However, cells do not always respond to steroids in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ef77acf0d771ae72d1e332cf91d493
https://doi.org/10.1165/rcmb.2007-0079oc
https://doi.org/10.1165/rcmb.2007-0079oc
Publikováno v:
Journal of cellular physiology
Asthma and chronic obstructive pulmonary disease (COPD) are characterized by chronic airway inflammation and major structural lung tissue changes including increased extracellular matrix (ECM) deposition. Inhaled corticosteroids and long-acting beta(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0d42c4d5127635c3ae5099c4e5e89e
Publikováno v:
RESPIRATORY RESEARCH
Respiratory Research, Vol 11, Iss 1, p 145 (2010)
Respiratory Research
Respiratory Research, Vol 11, Iss 1, p 145 (2010)
Respiratory Research
Background Airway wall remodelling is an important pathology of asthma. Growth factor induced airway smooth muscle cell (ASMC) proliferation is thought to be the major cause of airway wall thickening in asthma. Earlier we reported that Dimethylfumara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33e723ce75a4215a6400c7965df2cac
https://doi.org/10.1186/1465-9921-11-145
https://doi.org/10.1186/1465-9921-11-145
Autor:
Michel P, Bihl, Kirsten, Laule-Kilian, Lukas, Bubendorf, Robert M, Rutherford, Florent, Baty, Jeanne, Kehren, Emel, Eryüksel, Frank, Staedtler, Jing Qing, Yang, Stephanie, Goulet, John J, Gilmartin, Michael, Tamm, Martin H, Brutsche
Publikováno v:
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 23(1)
Sarcoidosis is a chronic granulomatous disorder of unknown etiology. In most patients the disease is self-limited, although for reasons unclear, others progress or die from progressive organ fibrosis. Growth factors have been implicated in the pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95cd7338f071daf944f4c4dd29ff94c1
https://pubmed.ncbi.nlm.nih.gov/16933469
https://pubmed.ncbi.nlm.nih.gov/16933469