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pro vyhledávání: '"Stephanie Fieve"'
Autor:
Anuradha Surendra, Nichole K. Escalante, Susan J. Robertson, Stephanie Fieve, Qiaochu Lin, David S. Guttman, Dana J. Philpott, Catherine J. Streutker, Cynthia X. Guo, Thierry Mallevaey, Thirumahal Selvanantham
Publikováno v:
The Journal of Immunology. 197:4464-4472
NKT cells are unconventional T cells that respond to self and microbe-derived lipid and glycolipid Ags presented by the CD1d molecule. Invariant NKT (iNKT) cells influence immune responses in numerous diseases. Although only a few studies have examin
Autor:
Thierry Mallevaey, Thirumahal Selvanantham, Stephanie Fieve, Dana J. Philpott, Nichole K. Escalante, Stephen E. Girardin, Mayra Cruz Tleugabulova
Publikováno v:
The Journal of Immunology. 191:5646-5654
Invariant NKT (iNKT) cells act at the crossroad between innate and adaptive immunity and are important players in the defense against microbial pathogens. iNKT cells can detect pathogens that trigger innate receptors (e.g., TLRs, Rig-I, Dectin-1) wit
Autor:
June Ereño-Orbea, Jean-Philippe Julien, Paul B. Savage, Shenglou Deng, Nichole K. Escalante, Mayra Cruz Tleugabulova, Stephanie Fieve, Thierry Mallevaey
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(10)
Invariant NKT (iNKT) cells develop and differentiate in the thymus, segregating into iNKT1/2/17 subsets akin to Th1/2/17 classical CD4+ T cells; however, iNKT TCRs recognize Ags in a fundamentally different way. How the biophysical parameters of iNKT