Výsledky vyhledávání - "Stephanie Everts"

Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma

Autor: Thomas Hawthorne, David M. Barris, Jonathan Gill, David S. Geller, Stephanie Everts, Peter J. Houghton, Michael Roth, Richard Gorlick, E. Anders Kolb, Vicky Kuo, Sajida Piperdi

Publikováno v: Pediatric Blood & Cancer. 63:32-38

Background Cure rates for children and young adults with osteosarcoma have remained stagnant over the past three decades. Targeting glycoprotein non-metastatic b (GPNMB) with the antibody-drug conjugate glembatumumab vedotin has improved outcomes for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0b9b5a90087d08c812786d22f469b5d
https://doi.org/10.1002/pbc.25688

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Context-dependent calcium signaling in encephalitogenic T cells – an in vivo two-photon imaging study

Autor: Stephanie Everts, Nikolaos I. Kyratsous, Ingo Bartholomäus, Guokun Zhang, Marija Pesic, Joanna M. Watt, Naoto Kawakami, Miriam Wörner, Ping Fang, Reinhard Hohlfeld, H. Wekerle, Marsilius Mues, Joachim W. Ellwart, Isabel J. Bauer, Barry V. L. Potter

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proc. Natl. Acad. Sci. U.S.A. 114, E6381-E6389 (2017)

In experimental autoimmune encephalitis (EAE), autoimmune T cells are activated in the periphery before they home to the CNS. On their way, the T cells pass through a series of different cellular milieus where they receive signals that instruct them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b476f2bc673a22acb3cea6e6db102b
http://ora.ox.ac.uk/objects/uuid:

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Single Dose Pharmacokinetics of Oral Tenofovir in Plasma, Peripheral Blood Mononuclear Cells, Colonic Tissue, and Vaginal Tissue

Autor: Ying Jun Cao, Rahul P. Bakshi, Edward J. Fuchs, Craig W. Hendrix, Jean Anderson, Stephanie Everts, Steven R. Tannenbaum, Nicolette A. Louissaint, Rosa G. Liberman, Paul L. Skipper, Sridhar Nimmagadda

Publikováno v: AIDS Research and Human Retroviruses. 29:1443-1450

HIV seroconversion outcomes in preexposure prophylaxis (PrEP) trials of oral tenofovir (TFV)-containing regimens are highly sensitive to drug concentration, yet less-than-daily dosing regimens are under study. Description of TFV and its active moiety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb81297eeca61940f65e446b39df18b
https://doi.org/10.1089/aid.2013.0044

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Safety, Tolerability, and Pharmacokinetics of the HIV Integrase Inhibitor Dolutegravir Given Twice Daily With Rifampin or Once Daily With Rifabutin

Autor: Ivy Song, Amanda Peppercorn, Elizabeth Purdy, Shuguang Chen, Stephen C. Piscitelli, Kelly E. Dooley, Charles Flexner, Julie Borland, Patrick Sayre, Stephanie Everts

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 62:21-27

Background Cotreatment of tuberculosis (TB) and HIV among coinfected patients is now the standard of care. Rifampin (RIF) is a standard part of TB treatment but is a potent inducer of drug metabolizing enzymes. This study evaluated the effect of RIF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180716e000c9c394608c4d2e1ebde4ec
https://doi.org/10.1097/qai.0b013e318276cda9

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Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma

Autor: Michael, Roth, David M, Barris, Sajida, Piperdi, Vicky, Kuo, Stephanie, Everts, David, Geller, Peter, Houghton, E Anders, Kolb, Thomas, Hawthorne, Jonathan, Gill, Richard, Gorlick

Publikováno v: Pediatric bloodcancer. 63(1)

Cure rates for children and young adults with osteosarcoma have remained stagnant over the past three decades. Targeting glycoprotein non-metastatic b (GPNMB) with the antibody-drug conjugate glembatumumab vedotin has improved outcomes for patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fcef3323a63350a42d2909bdf3e8824
https://pubmed.ncbi.nlm.nih.gov/26305408

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Pharmacokinetic effect of AMD070, an Oral CXCR4 antagonist, on CYP3A4 and CYP2D6 substrates midazolam and dextromethorphan in healthy volunteers

Autor: Priscilla Chee, Gary Calandra, Craig W. Hendrix, Myaing M. Nyunt, Ron MacFarland, Stephanie Everts, Stephen Becker, Robert J. Scarborough

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 47(5)

Background: Many antiretroviral drugs used in HIV care involve complex drug metabolism by CYP3A4 and CYP2D6 enzymes, and drug interactions are problematic clinically. AMD070, a novel entry inhibitor, is an inhibitor of X4-tropic HIV virus. In vitro d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94850c41648aa2a3d293e178a0a8c3b2
https://pubmed.ncbi.nlm.nih.gov/18362694

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