Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Stephanie E. Weissinger"'
Autor:
Stephanie E. Weissinger, Rucha Dugge, Miriam Disch, Thomas F. Barth, Johannes Bloehdorn, Malena Zahn, Ralf Marienfeld, Andreas Viardot, Peter Möller
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 688-697 (2022)
Abstract Primary extranodal diffuse large B‐cell lymphoma (PE‐DLBCL) is a heterogeneous subgroup of DLBCL. We investigated the prevalence and prognostic value of surface expression of PD‐L1, PD1, and CD30, copy number of 9p24.1 (PD‐L1 region)
Externí odkaz:
https://doaj.org/article/5b94006d842a43458095cdf8d6518307
Autor:
Johannes Doescher, Adrian von Witzleben, Konstantinos Boukas, Stephanie E. Weissinger, Gareth J. Thomas, Simon Laban, Jaya Thomas, Thomas K. Hoffmann, Christian H. Ottensmeier
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chemoradiotherapy (CRT) is a standard treatment for advanced head and neck squamous cell carcinoma (HNSCC). Unfortunately, not all patients respond to this therapy and require further treatment, either salvage surgery or palliative therapy. The addit
Externí odkaz:
https://doaj.org/article/0f6a2dfd86bf46f089d4d00e59c62b60
Autor:
Annika C. Betzler, Hannah Strobel, Tsima Abou Kors, Jasmin Ezić, Kristina Lesakova, Ronja Pscheid, Ninel Azoitei, Johanna Sporleder, Anna-Rebekka Staufenberg, Robert Drees, Stephanie E. Weissinger, Jens Greve, Johannes Doescher, Marie-Nicole Theodoraki, Patrick J. Schuler, Simon Laban, Toshiro Kibe, Michiko Kishida, Shosei Kishida, Christian Idel, Thomas K. Hoffmann, Marialuisa Lavitrano, Emanuela Grassilli, Cornelia Brunner
Publikováno v:
Cancers, Vol 15, Iss 1, p 310 (2023)
Here, we describe the expression of Bruton’s Tyrosine Kinase (BTK) in head and neck squamous cell carcinoma (HNSCC) cell lines as well as in primary HNSCC samples. BTK is a kinase initially thought to be expressed exclusively in cells of hematopoie
Externí odkaz:
https://doaj.org/article/c02d28b243bd45a3bd0efcf9f22ad5b1
Autor:
Johannes Doescher, Moritz Meyer, Christoph Arolt, Alexander Quaas, Jens Peter Klußmann, Philipp Wolber, Agnes Bankfalvi, Hans-Ulrich Schildhaus, Tobias Bastian, Stephan Lang, Simon Laban, Patrick J. Schuler, Cornelia Brunner, Thomas K. Hoffmann, Stephanie E. Weissinger
Publikováno v:
Cancers, Vol 14, Iss 6, p 1383 (2022)
Adenoid cystic carcinoma (ACC) is a rare malignancy in the head and neck. The prognosis remains poor and late recurrences often occur after 5 years and later. To date, there are no reliable prognostic markers for ACC. In several solid tumors, tertiar
Externí odkaz:
https://doaj.org/article/2b35bc187a814cca9bad673a926e749b
Autor:
Lisa K. Puntigam, Sandra S. Jeske, Marlies Götz, Jochen Greiner, Simon Laban, Marie-Nicole Theodoraki, Johannes Doescher, Stephanie E. Weissinger, Cornelia Brunner, Thomas K. Hoffmann, Patrick J. Schuler
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5181 (2020)
Endogenous control mechanisms, including immune checkpoints and immunosuppressive cells, are exploited in the process of tumorigenesis to weaken the anti-tumor immune response. Cancer treatment by chemotherapy or immune checkpoint inhibition can lead
Externí odkaz:
https://doaj.org/article/853012bad4b647d1a617dfb8c2883e8d
Autor:
Jochen K. Lennerz, Roberto Salgado, Grace E. Kim, Sahussapont Joseph Sirintrapun, Julia C. Thierauf, Ankit Singh, Iciar Indave, Adam Bard, Stephanie E. Weissinger, Yael K. Heher, Monica E. de Baca, Ian A. Cree, Shannon Bennett, Anna Carobene, Tomris Ozben, Lauren L. Ritterhouse
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 61:544-557
Background Laboratory medicine has reached the era where promises of artificial intelligence and machine learning (AI/ML) seem palpable. Currently, the primary responsibility for risk-benefit assessment in clinical practice resides with the medical d
Autor:
Alexander Kleger, Pierre-Olivier Frappart, Thomas Seufferlein, Peter Möller, Hans A. Kestler, Sebastian Wiese, Volker Rasche, Konstantin M.J. Sparrer, Ewa K. Kaminska, Axel Fürstberger, Li Hao, Ninel Azoitei, Thomas J. Ettrich, André Lechel, Caterina Prelli Bozzo, Jeanette Scheible, Karolin Walter, Lukas Perkhofer, Elodie Roger, Stephanie E. Weissinger, Heike Wiese, Johann Gout, Frank Arnold
Pancreatic ductal adenocarcinoma (PDAC) still presents with a dismal prognosis despite intense research. Better understanding of cellular homeostasis could identify druggable targets to improve therapy. Here we propose RAD50-interacting protein 1 (RI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81c0c354220e7de74d24c2ff7f54301
https://doi.org/10.1158/0008-5472.c.6513184.v1
https://doi.org/10.1158/0008-5472.c.6513184.v1
Autor:
Alexander Kleger, Pierre-Olivier Frappart, Thomas Seufferlein, Peter Möller, Hans A. Kestler, Sebastian Wiese, Volker Rasche, Konstantin M.J. Sparrer, Ewa K. Kaminska, Axel Fürstberger, Li Hao, Ninel Azoitei, Thomas J. Ettrich, André Lechel, Caterina Prelli Bozzo, Jeanette Scheible, Karolin Walter, Lukas Perkhofer, Elodie Roger, Stephanie E. Weissinger, Heike Wiese, Johann Gout, Frank Arnold
Contains a more detailed method section as well as all additional supplementary figures S1 to S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3053d93096593f057df6b3f3dc3cf5
https://doi.org/10.1158/0008-5472.22428880.v1
https://doi.org/10.1158/0008-5472.22428880.v1
Autor:
Stephanie E. Weissinger, N. Zeke Georgantas, Julia C. Thierauf, Rebecca Pellerin, Emma Gardecki, Stephanie Kühlinger, Lauren L. Ritterhouse, Peter Möller, Jochen K. Lennerz
Publikováno v:
Laboratory Investigation. 103:100062
Autor:
Sandra Wiedenmann, Stefanie M. Hauck, Alexander Kleger, Michael Sterr, Thomas Seufferlein, Markus Breunig, Peter Möller, J Merkle, Meike Hohwieler, Christine von Toerne, Michel Moussus, Stephanie E. Weissinger, Tihomir Georgiev, Matthias Meier, Lucas A. Schulte, Heiko Lickert
Publikováno v:
Nat. Bio. Eng. 5, 897-913 (2021)
Creating in vitro models of diseases of the pancreatic ductal compartment requires a comprehensive understanding of the developmental trajectories of pancreas-specific cell types. Here we report the single-cell characterization of the differentiation