Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stephanie E. Spence"'
Autor:
John C. Crabbe, Angela R. Ozburn, Robert J. Hitzemann, Stephanie E. Spence, Wyatt R. Hack, Jason P. Schlumbohm, Pamela Metten
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 4, Iss , Pp 100061- (2020)
Alcohol use disorders (AUDs) are prevalent, and are characterized by binge-like drinking, defined by patterns of focused drinking where dosages ingested in 2–4 h reach intoxicating blood alcohol levels (BALs). Current medications are few and com
Externí odkaz:
https://doaj.org/article/932849e6259a4bc9b698711fb648c549
Autor:
John C. Crabbe, Pamela Metten, Antonia M. Savarese, Angela R. Ozburn, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack
Publikováno v:
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Two independent lines of High Drinking in the Dark (HDID-1, HDID-2) mice have been bred to reach high blood alcohol levels after a short period of binge-like ethanol drinking. Male mice of both lines were shown to have reduced sensitivity to develop
Externí odkaz:
https://doaj.org/article/c76b96e7c61040148f41afe1a2e5fb6f
Autor:
Angela R. Ozburn, John C. Crabbe, Pamela Metten, Antonia Savarese, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack
Publikováno v:
Brain Sciences
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Volume 9
Issue 1
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Volume 9
Issue 1
Two independent lines of High Drinking in the Dark (HDID-1, HDID-2) mice have been bred to reach high blood alcohol levels after a short period of binge-like ethanol drinking. Male mice of both lines were shown to have reduced sensitivity to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b2253819c60084cd61d722c3ad9325
http://europepmc.org/articles/PMC6356868
http://europepmc.org/articles/PMC6356868
Autor:
Jason P. Schlumbohm, Angela R. Ozburn, John C. Crabbe, Robert Hitzemann, Pamela Metten, Wyatt R. Hack, Stephanie E. Spence
Publikováno v:
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100061-(2020)
Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100061-(2020)
Alcohol use disorders (AUDs) are prevalent, and are characterized by binge-like drinking, defined by patterns of focused drinking where dosages ingested in 2–4 h reach intoxicating blood alcohol levels (BALs). Current medications are few and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545e35a76cb1e05923f987d862178a7a
https://doi.org/10.1016/j.bbih.2020.100061
https://doi.org/10.1016/j.bbih.2020.100061
Autor:
Lawrence C. Huang, John C. Crabbe, Jason P. Schlumbohm, Gian D. Greenberg, Wyatt R. Hack, Pamela Metten, Stephanie E. Spence
Publikováno v:
Alcohol (Fayetteville, N.Y.). 68
Despite acceptance that risk for alcohol-use disorder (AUD) has a large genetic component, the identification of genes underlying various components of risk for AUD has been hampered in humans, in part by the heterogeneity of expression of the phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ad50f6836decd5f7e9b12ef981290d
https://pubmed.ncbi.nlm.nih.gov/29427828
https://pubmed.ncbi.nlm.nih.gov/29427828
Autor:
Angela R. Ozburn, Jason P. Schlumbohm, John C. Crabbe, Lawrence C. Huang, Amanda M. Barkley-Levenson, Stephanie E. Spence, Wyatt R. Hack, Pamela Metten
Publikováno v:
Pharmacology, biochemistry, and behavior. 160
Background There is a serious public health need for better understanding of alcohol use disorder disease mechanisms and for improved treatments. At this writing, only three drugs are approved by the Food and Drug Administration as medications to tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772da906066c7f6eda3ddac873e13fde
https://pubmed.ncbi.nlm.nih.gov/28827047
https://pubmed.ncbi.nlm.nih.gov/28827047
Autor:
Amanda M. Barkley-Levenson, Pamela Metten, Andy J. Cameron, Stephanie E. Spence, Lawrence C. Huang, Matthew M. Ford, Jason P. Schlumbohm, John C. Crabbe, Tamara J. Phillips, John K. Belknap
Publikováno v:
Genes, Brain and Behavior. 13:236-246
Drinking in the dark (DID) is a limited access ethanol-drinking phenotype in mice. High Drinking in the Dark (HDID-1) mice have been bred for 27 selected generations (S27) for elevated blood ethanol concentrations (BECs) after a 4-h period of access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f55a29f2b786029adb539b16138559
https://doi.org/10.1111/gbb.12105
https://doi.org/10.1111/gbb.12105
Autor:
Lawrence C. Huang, Andy J. Cameron, Jason P. Schlumbohm, John C. Crabbe, Stephanie E. Spence, Pamela Metten, Amanda M. Barkley-Levenson
Publikováno v:
Alcohol. 47:381-389
Withdrawal Seizure-Prone (WSP) and Withdrawal Seizure-Resistant (WSR) mouse lines were bidirectionally selectively bred, respectively, to have severe or mild ethanol withdrawal handling-induced convulsions (HICs) after cessation of 3 days of ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1075be53cc0eb6390f1f711b1c536d6e
https://doi.org/10.1016/j.alcohol.2013.05.002
https://doi.org/10.1016/j.alcohol.2013.05.002
Autor:
Ovidiu D. Iancu, Jason P. Schlumbohm, Priscila Darakjian, Pamela Metten, Denesa Oberbeck, Robert Hitzemann, Stephanie E. Spence, Shannon K. McWeeney, John C. Crabbe
Publikováno v:
Alcohol (Fayetteville, N.Y.). 60
Among animals at risk for excessive ethanol consumption such as the HDID selected mouse lines, there is considerable individual variation in the amount of ethanol consumed and the associated blood ethanol concentrations (BECs). For the HDID lines, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688477e43bb8cf3eaf033163a9325d8a
https://pubmed.ncbi.nlm.nih.gov/28442218
https://pubmed.ncbi.nlm.nih.gov/28442218
Autor:
John C. Crabbe, Lawrence C. Huang, Stephanie E. Spence, Jason P. Schlumbohm, Gian D. Greenberg, Angela R. Ozburn, Pamela Metten
Withdrawal after chronic ethanol (EtOH) affects body temperature, goal-directed behavior and motor function in mice and increases general central nervous system excitability. Nest-building tests have been used to assay these states but to this point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeea54f18f652e6a17811acd24231d1
https://europepmc.org/articles/PMC5456259/
https://europepmc.org/articles/PMC5456259/
