Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Stephanie E Easthope"'
Autor:
Stephanie E Easthope, Dean M Robinson
Publikováno v:
BioDrugs. 19:327-343
Darbepoetin alfa (Aranesp), Nespo) is an amino acid substituted analog of human erythropoietin (EPO) that promotes erythrocyte survival, proliferation, and differentiation. Approved in Europe and the US for the treatment of anemia associated with chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069aa302d495e702a6a491cf865d5915
https://doi.org/10.2165/00063030-200519050-00006
https://doi.org/10.2165/00063030-200519050-00006
Publikováno v:
American Journal of PharmacoGenomics. 5:133-136
Gefitinib (Iressa), the first commercially available epidermal growth factor receptor-tyrosine kinase (EGFR-TK) inhibitor, is indicated in the management of patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC). However, app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c61e49d7bee54d39a58067f070d0a2
https://doi.org/10.2165/00129785-200505020-00006
https://doi.org/10.2165/00129785-200505020-00006
Publikováno v:
Drugs. 64:2475-2492
Gefitinib (Iressa), the first commercially available epidermal growth factor receptor-tyrosine kinase (EGFR-TK) inhibitor, is indicated in the management of patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC). However, app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a7bb887bc02c61680cd1fa6db8708b
https://doi.org/10.2165/00003495-200464210-00008
https://doi.org/10.2165/00003495-200464210-00008
Publikováno v:
Drugs & Aging. 20:857-864
Oxybutynin binds to the M(3) muscarinic receptors on the detrusor muscle of the bladder, preventing acetylcholinergic activation and relaxing the muscle. The transdermal system delivers oxybutynin over a 3- to 4-day period after application to intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee47b91cb82cf715cb55d8678b248d7
https://doi.org/10.2165/00002512-200320110-00007
https://doi.org/10.2165/00002512-200320110-00007
Publikováno v:
Drugs & Aging. 19:231-248
Bimatoprost, a synthetic prostamide analogue, is a new ocular hypotensive agent indicated for the second-line treatment of open-angle glaucoma and ocular hypertension. The drug is formulated as a 0.03% ophthalmic solution. Bimatoprost lowers intraocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622364ab20f383d4cfb94b8437f4c8be
https://doi.org/10.2165/00002512-200219030-00008
https://doi.org/10.2165/00002512-200219030-00008
Autor:
Stephanie E Easthope, Blair Jarvis
Publikováno v:
Drugs. 62:1253-1287
Candesartan cilexetil is converted to the angiotensin II receptor antagonist candesartan during absorption from the gastrointestinal tract. The selective and competitive binding of candesartan to the angiotensin II type 1 (ATi) receptor prevents bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44c4525a9c89bbeb31a3152a6f46ea4
https://doi.org/10.2165/00003495-200262080-00016
https://doi.org/10.2165/00003495-200262080-00016
Autor:
Stephanie E Easthope, Karen L. Goa
Publikováno v:
CNS Drugs. 15:969-976
black triangle Frovatriptan, a new serotonin receptor agonist developed for the acute treatment of migraine, has high affinity for serotonin 5-HT1B and 5-HT1D receptor subtypes and is a potent stimulator of contraction in human basilar arteries. blac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d649e8d62367e646a24adcf2e4b035ab
https://doi.org/10.2165/00023210-200115120-00006
https://doi.org/10.2165/00023210-200115120-00006
Publikováno v:
Drugs. 66(3)
0.4% Nitroglycerin ointment is an intra-anal formulation of nitroglycerin (glyceryl trinitrate) indicated for the treatment of chronic anal fissure pain.black triangle Nitroglycerin is a nitric oxide (NO) donor, which reduces the increased anal canal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bdf4e9533f926da2b750968bac2d2c
https://pubmed.ncbi.nlm.nih.gov/16526822
https://pubmed.ncbi.nlm.nih.gov/16526822
Publikováno v:
Drugs. 66(1)
Pioglitazone is an antihyperglycaemic agent that, in the presence of insulin resistance, increases hepatic and peripheral insulin sensitivity, thereby inhibiting hepatic gluconeogenesis and increasing peripheral and splanchnic glucose uptake. Pioglit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5980d516f2adb5e96ceaea3d55559550
https://pubmed.ncbi.nlm.nih.gov/16398569
https://pubmed.ncbi.nlm.nih.gov/16398569
Publikováno v:
CNS drugs. 19(11)
Rotigotine is a nonergolinic dopamine D3/D2/D1 receptor agonist delivered via a transdermal system and has been evaluated for the treatment of idiopathic Parkinson's disease. Patients with early Parkinson's disease receiving rotigotine monotherapy ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34606b4c0201b004824d19a4f18cdd6d
https://pubmed.ncbi.nlm.nih.gov/16268667
https://pubmed.ncbi.nlm.nih.gov/16268667