Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stephanie E A Burnell"'
Autor:
Stephanie E A Burnell, Samantha Spencer-Harty, Suzie Howarth, Owen Bodger, Howard Kynaston, Claire Morgan, Shareen H Doak
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220456 (2019)
Prostate cancer is the second most common cancer diagnosed in men worldwide; however, few patients are affected by clinically significant disease within their lifetime. Unfortunately, the means to discriminate between patients with indolent disease a
Externí odkaz:
https://doaj.org/article/ac9b517c50d74ea3b85427fa547d2222
Autor:
Zita M. Jessop, Ayesha Al-Sabah, Irina N. Simoes, Stephanie E. A. Burnell, Ina Laura Pieper, Catherine A. Thornton, Iain S. Whitaker
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background Since cartilage-derived stem/progenitor cells (CSPCs) were first identified in articular cartilage using differential adhesion to fibronectin, their self-renewal capacity and niche-specific lineage preference for chondrogenesis ha
Externí odkaz:
https://doaj.org/article/c71446608b554615894f979cd390f9a3
Cancer immunotherapy represents a significant breakthrough in cancer treatment mainly due to the ability to harness the activities of cancer-specific T cells. Despite this, most cancers remain resistant to T cell attack. Many reasons have been propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a5e76097912101aa97111ddd196dc1
Autor:
Charlotte Young, Lucy C. Fairclough, Andrew D. Westwell, Kerry Roberts, Kate Davies, Thomas Tozer, Stephanie E A Burnell, Paddy Tighe, Tara Rees, Amanda Jackson, B. Paul Morgan, Awen Gallimore, Martin J. Scurr, Michelle Somerville, Mererid Evans, Andrew James Godkin, George Lippiatt, Wioleta M. Zelek, Mark R. Wills, Helen Lawton, Lorenzo Capitani
Publikováno v:
Immunology
Accurate assessment of SARS‐CoV‐2 immunity is critical in evaluating vaccine efficacy and devising public health policies. Whilst the exact nature of effective immunity remains incompletely defined, SARS‐CoV‐2‐specific T‐cell responses ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d98df614d6784a18360ac8e997abea
http://europepmc.org/articles/PMC8653009
http://europepmc.org/articles/PMC8653009
Autor:
Andrew James Godkin, Alan L. Parker, Elise Moses, Rebecca J. Bayliss, Georgina H. Mason, Alicia Teijeira Crespo, Lorenzo Capitani, Awen Gallimore, James A. Davies, Stephanie E A Burnell
Publikováno v:
Immunology
Oncolytic viruses possess the ability to infect, replicate and lyse malignantly transformed tumour cells. This oncolytic activity amplifies the therapeutic advantage and induces a form of immunogenic cell death, characterized by increased CD8 + T‐c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8914e2f9ae1ff06e891522d1b1dce3ca
Autor:
Stephanie E A Burnell, Lorenzo Capitani, Bruce J MacLachlan, Georgina H Mason, Awen M Gallimore, Andrew Godkin
Publikováno v:
Immunotherapy advances. 2(1)
Despite three decades of research to its name and increasing interest in immunotherapies that target it, LAG-3 remains an elusive co-inhibitory receptor in comparison to the well-established PD-1 and CTLA-4. As such, LAG-3 targeting therapies have ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819e5445403ad7717dfa0b6d2dd0d01c
https://pubmed.ncbi.nlm.nih.gov/35265944
https://pubmed.ncbi.nlm.nih.gov/35265944
Autor:
Thomas Tozer, Kate Davies, Lucy C. Fairclough, Martin J. Scurr, Michelle Somerville, Kerry Roberts, Andrew James Godkin, Mererid Evans, George Lippiatt, Andrew D. Westwell, Tara Rees, Mark R. Wills, Helen Lawton, Stephanie E A Burnell, Awen Gallimore, Amanda Jackson, Wioleta M. Zelek, Lorenzo Capitani, Charlotte Aimee Young, B. Paul Morgan
Accurate assessment of SARS-CoV-2 immunity in the population is critical to evaluating vaccine efficacy and devising public health policies. Whilst the exact nature of effective immunity remains incompletely defined, SARS-CoV-2-specific T cell respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c11330d1aecb09fe1f9bfa9265e9e1
https://doi.org/10.1101/2021.06.02.21258218
https://doi.org/10.1101/2021.06.02.21258218
Autor:
Irina N. Simoes, Ina Laura Pieper, Catherine A. Thornton, Stephanie E. A. Burnell, Iain S. Whitaker, Zita M. Jessop, Ayesha Al-Sabah
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Since cartilage-derived stem/progenitor cells (CSPCs) were first identified in articular cartilage using differential adhesion to fibronectin, their self-renewal capacity and niche-specific lineage preference for chondrogenesis have propel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b84fa50010b23e22dd5e25cc45d9fc6
https://doi.org/10.1186/s13287-020-01663-1
https://doi.org/10.1186/s13287-020-01663-1
Autor:
Claire Morgan, Shareen H. Doak, Howard Kynaston, Samantha Spencer-Harty, Owen Bodger, Suzie Howarth, Stephanie E. A. Burnell
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Six-transmembrane epithelial antigen of the prostate-2 (STEAP2) expression is increased in prostate cancer when compared to normal prostate, suggesting STEAP2 may drive prostate cancer progression. This study aimed to establish the functional role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc64e3863de14614a853932fe886ed05
http://link.springer.com/article/10.1038/s41598-018-24655-x
http://link.springer.com/article/10.1038/s41598-018-24655-x
Autor:
Yuan Chen, Stephanie E A Burnell, Michael M. Davies, Rachel Hargest, Adam Christian, Andrew James Godkin, Emma Campbell, Robert Andrews, Simon Phillips, Awen Gallimore, Sarah Hulin-Curtis, Alan L. Parker, Michelle Somerville, Alexander Greenshields-Watson, James A. Davies, Martin J. Scurr, Kevin E. Ashelford, Richard J. Stanton
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(13)
Purpose: Broadly expressed, highly differentiated tumor-associated antigens (TAA) can elicit antitumor immunity. However, vaccines targeting TAAs have demonstrated disappointing clinical results, reflecting poor antigen selection and/or immunosuppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946d2bfefb2779dc28f86c442caca8ff
https://pubmed.ncbi.nlm.nih.gov/32122920
https://pubmed.ncbi.nlm.nih.gov/32122920