Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Stephanie C Gantz"'
Publikováno v:
eLife, Vol 10 (2021)
Ultrapotent chemogenetics, including the chloride-permeable inhibitory PSAM4-GlyR receptor, were recently proposed as a powerful strategy to selectively control neuronal activity in awake, behaving animals. We aimed to validate the inhibitory functio
Externí odkaz:
https://doaj.org/article/7449ab2676034253b79760799f82b4f7
Publikováno v:
eLife, Vol 9 (2020)
The dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. Action potential firing of serotonin dorsal raphe neurons is driven via α1-adrenergic receptors (α1-AR) activati
Externí odkaz:
https://doaj.org/article/463104f2681c4d35bedabc965ca4decf
Autor:
Aleigha Gugel, Stephanie C. Gantz
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Publikováno v:
EMBO reports.
Publikováno v:
Biophysical Journal.
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 944-954 (2015)
Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson’s disease (PD) and psychiatric disorders. L-DOPA, the leading treatment of PD, facilitates the production and release o
Externí odkaz:
https://doaj.org/article/9b8633881a464208b3292526d35a81d2
Autor:
Daniel S. Copeland, Stephanie C. Gantz
Previously, using electrophysiological recordings from adult male and female mouse brain slices containing the dorsal raphe nucleus, we showed that GluD1R channels carry ionic current and are modulated via activation of Gαq-coupled α1-adrenergic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1de2c292130ce89b2f9b8752bff6766
https://doi.org/10.1101/2022.01.20.477055
https://doi.org/10.1101/2022.01.20.477055
Autor:
Daniel S, Copeland, Stephanie C, Gantz
Publikováno v:
Neuropsychopharmacology
Parvalbumin-expressing fast-spiking interneurons (PV-INs) within feedforward microcircuits in the nucleus accumbens (NAc) coordinate goal-directed motivational behavior. Feedforward inhibition of medium spiny projection neurons (MSNs) is initiated by
Autor:
Stephanie C Gantz, Brooks G Robinson, David C Buck, James R Bunzow, Rachael L Neve, John T Williams, Kim A Neve
Publikováno v:
eLife, Vol 4 (2015)
D2 autoreceptors regulate dopamine release throughout the brain. Two isoforms of the D2 receptor, D2S and D2L, are expressed in midbrain dopamine neurons. Differential roles of these isoforms as autoreceptors are poorly understood. By virally express
Externí odkaz:
https://doaj.org/article/8ad20fd828744c2a90d9e5d99be6908d
Autor:
Colin H, Peters, Pin W, Liu, Stefano, Morotti, Stephanie C, Gantz, Eleonora, Grandi, Bruce P, Bean, Catherine, Proenza
Publikováno v:
Proc Natl Acad Sci U S A
Sinoatrial node myocytes (SAMs) act as cardiac pacemaker cells by firing spontaneous action potentials (APs) that initiate each heartbeat. The funny current (I(f)) is critical for the generation of these spontaneous APs; however, its precise role dur