Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephanie Broome"'
Autor:
Elizabeth Spangenberg, Paul L. Severson, Lindsay A. Hohsfield, Joshua Crapser, Jiazhong Zhang, Elizabeth A. Burton, Ying Zhang, Wayne Spevak, Jack Lin, Nicole Y. Phan, Gaston Habets, Andrey Rymar, Garson Tsang, Jason Walters, Marika Nespi, Parmveer Singh, Stephanie Broome, Prabha Ibrahim, Chao Zhang, Gideon Bollag, Brian L. West, Kim N. Green
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Genetics implicate microglia in Alzheimer’s disease pathogenesis, but their roles remain unclear. Here, the authors find that microglial depletion in a mouse model of Alzheimer’s disease impairs plaque formation and that Aβ-induced changes in ne
Externí odkaz:
https://doaj.org/article/ab83dec7482d44a28b96b168ea75f0ff
Autor:
Gaston Habets, Parmveer Singh, Gideon Bollag, Brian L. West, Lindsay A. Hohsfield, Andrey Rymar, Prabha N. Ibrahim, Stephanie Broome, Joshua D. Crapser, Garson Tsang, Elizabeth E. Spangenberg, Marika Nespi, Elizabeth A. Burton, Paul Severson, Jason Walters, Kim N. Green, Chao Zhang, Jack Lin, Jiazhong Zhang, Wayne Spevak, Ying Zhang, Nicole Y. Phan
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Nature Communications
Many risk genes for the development of Alzheimer’s disease (AD) are exclusively or highly expressed in myeloid cells. Microglia are dependent on colony-stimulating factor 1 receptor (CSF1R) signaling for their survival. We designed and synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed40cee7378de96501838a791a1537ee
https://escholarship.org/uc/item/6062s7cq
https://escholarship.org/uc/item/6062s7cq
Autor:
Georg Widera, Stephanie Broome, Michael J. Roy, Robert R. Edelman, Carol O. Tacket, William F. Swain
Publikováno v:
Vaccine. 17(22)
This study was designed to determine the safety and immunogenicity in volunteers of a DNA vaccine consisting of a plasmid encoding hepatitis B surface antigen delivered by the PowderJect XR1 gene delivery system into human skin. Seven healthy adult v