Diabetes mellitus and cognition: A pathway analysis in the MEMENTO cohort

Autor: Eric, Frison, Cecile, Proust-Lima, Jean-Francois, Mangin, Marie-Odile, Habert, Stephanie, Bombois, Pierre-Jean, Ousset, Florence, Pasquier, Olivier, Hanon, Claire, Paquet, Audrey, Gabelle, Mathieu, Ceccaldi, Cédric, Annweiler, Pierre, Krolak-Salmon, Yannick, Béjot, Catherine, Belin, David, Wallon, Mathilde, Sauvee, Emilie, Beaufils, Isabelle, Bourdel-Marchasson, Isabelle, Jalenques, Marie, Chupin, Geneviève, Chêne, Carole, Dufouil, Jean, Zinszner

Publikováno v: Neurology
Neurology, 2021, 97 (8), pp.e836-e848. ⟨10.1212/WNL.0000000000012440⟩
Neurology, 2021, 2021, ⟨10.1212/WNL.0000000000012440⟩
Neurology, American Academy of Neurology, 2021, 2021, ⟨10.1212/WNL.0000000000012440⟩
article-version (Version of Record) 3

International audience; Objective: To assess the role of biomarkers of Alzheimer's Disease (AD), neurodegeneration and small vessel disease (SVD) as mediators in the association between diabetes mellitus and cognition.Methods: The study sample was de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::20981641a91a91ff17b43b0a83c438c0
https://hal.sorbonne-universite.fr/hal-03278377

Relevance of Follow-Up in Patients with Core Clinical Criteria for Alzheimer Disease and Normal CSF Biomarkers

Autor: Olivier Vercruysse, Claire Paquet, Audrey Gabelle, Xavier Delbeuck, Frederic Blanc, David Wallon, Julien Dumurgier, Eloi Magnin, Olivier Martinaud, Barbara Jung, Olivier Bousiges, Sylvain Lehmann, Constance Delaby, Muriel Quillard-Murain, Katell Peoc`h, Jean-Louis Laplanche, Elodie Bouaziz-Amar, Didier Hannequin, Bernard Sablonniere, Luc Buee, Jacques Hugon, Susanna Schraen, Florence Pasquier, Stephanie Bombois, null for the e-PLM group

Publikováno v: Current Alzheimer Research
Current Alzheimer Research, Bentham Science Publishers, 2018, 15 (7), pp.691-700. ⟨10.2174/1567205015666180110113238⟩
Current Alzheimer Research, 2018, 15 (7), pp.691-700. ⟨10.2174/1567205015666180110113238⟩

Background: Few patients with a normal cerebrospinal fluid (CSF) biomarker profile fulfill the clinical criteria for Alzheimer disease (AD). Objective: The aim of this study was to test the hypothesis of misdiagnoses for these patients. Method: Patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ef0170e4f68c4a83193351364b8de7
https://doi.org/10.2174/1567205015666180110113238

Validation study of 'Santé-Cerveau', a digital tool for early cognitive changes identification

Autor: Constance Lesoil, Stéphanie Bombois, Octave Guinebretiere, Marion Houot, Mahsa Bahrami, Marcel Levy, Rémy Genthon, Frédérique Bozon, Heidy Jean-Marie, Stéphane Epelbaum, Pierre Foulon, Nicolas Villain, Bruno Dubois

Publikováno v: Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)

Abstract Background There is a need for a reliable, easy-to-use, widely available, and validated tool for timely cognitive impairment identification. We created a computerized cognitive screening tool (Santé-Cerveau digital tool (SCD-T)) including v

Externí odkaz: https://doaj.org/article/8996b1a91c284e2986eb5611413b650e

Plasma lysosphingolipids in GRN-related diseases: Monitoring lysosomal dysfunction to track disease progression

Autor: Walid Khrouf, Dario Saracino, Benoit Rucheton, Marion Houot, Fabienne Clot, Daisy Rinaldi, Joana Vitor, Marie Huynh, Evelyne Heng, Dimitri Schlemmer, Florence Pasquier, Vincent Deramecourt, Sophie Auriacombe, Carole Azuar, Richard Levy, Stéphanie Bombois, Claire Boutoleau-Brétonnière, Jérémie Pariente, Mira Didic, David Wallon, Frédérique Fluchère, Stéphane Auvin, Imen Ben Younes, Yann Nadjar, Alexis Brice, Bruno Dubois, Dominique Bonnefont-Rousselot, Isabelle Le Ber, Foudil Lamari

Publikováno v: Neurobiology of Disease, Vol 181, Iss , Pp 106108- (2023)

GRN mutations are among the main genetic causes of frontotemporal dementia (FTD). Considering the progranulin involvement in lysosomal homeostasis, we aimed to evaluate if plasma lysosphingolipids (lysoSPL) are increased in GRN mutation carriers, and

Externí odkaz: https://doaj.org/article/74d41b87d2e9459a8fa3e729c04253b6

Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network

Autor: Mélanie Leroy, Maxime Bertoux, Emilie Skrobala, Elisa Mode, Catherine Adnet-Bonte, Isabelle Le Ber, Stéphanie Bombois, Pascaline Cassagnaud, Yaohua Chen, Vincent Deramecourt, Florence Lebert, Marie Anne Mackowiak, Adeline Rollin Sillaire, Marielle Wathelet, Florence Pasquier, Thibaud Lebouvier, the Méotis network

Publikováno v: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)

Abstract Background Due to heterogeneous clinical presentation, difficult differential diagnosis with Alzheimer’s disease (AD) and psychiatric disorders, and evolving clinical criteria, the epidemiology and natural history of frontotemporal lobar d

Externí odkaz: https://doaj.org/article/b634756d0e1a42a3a0dc64db05e21300