Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephanie Backer"'
Autor:
Elsa Rossignol, Lara Eid, Praveen Kumar Raju, Ludmilla Lokmane, Samuel Boris Tene Tadoum, Xiao Jiang, Karolanne Toulouse, Alexis Lupien-Meilleur, François Charron-Ligez, Asmaa Toumi, Stephanie Backer, Mathieu Lachance, Marisol Lavertu-Jolin, Marie Montseny, Jean-Claude Lacaille, Evelyne Bloch-Gallego
Recessive mutations in the TRIO gene are associated with intellectual deficiency (ID), autism spectrum disorder (ASD) and developmental epileptic encephalopathies (DEE). TRIO is a dual guanine nucleotide exchange factor (GEF) that activates Rac1, Cdc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122d11c9893b9b419ae75fdb59f866cf
https://doi.org/10.21203/rs.3.rs-2409410/v1
https://doi.org/10.21203/rs.3.rs-2409410/v1
Autor:
Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire
Publikováno v:
PLoS Genetics, Vol 19, Iss 6, p e1010781 (2023)
Four SIX homeoproteins display a combinatorial expression throughout embryonic developmental myogenesis and they modulate the expression of the myogenic regulatory factors. Here, we provide a deep characterization of their role in distinct mouse deve
Externí odkaz:
https://doaj.org/article/f895eb3224a746f8973f44c80b277f99
Autor:
Matthieu Dos Santos, Stéphanie Backer, Frédéric Auradé, Matthew Man-Kin Wong, Maud Wurmser, Rémi Pierre, Francina Langa, Marcio Do Cruzeiro, Alain Schmitt, Jean-Paul Concordet, Athanassia Sotiropoulos, F. Jeffrey Dilworth, Daan Noordermeer, Frédéric Relaix, Iori Sakakibara, Pascal Maire
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform content. Here the authors show that a super enhancer controls the spatiotemporal expression of the genes at the fast myosin heavy chain locus by DNA looping
Externí odkaz:
https://doaj.org/article/1e1732b409944febbd7c8c1cfe87a24b
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
Autor:
Matthieu Dos Santos, Stéphanie Backer, Benjamin Saintpierre, Brigitte Izac, Muriel Andrieu, Franck Letourneur, Frederic Relaix, Athanassia Sotiropoulos, Pascal Maire
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Whether skeletal muscle fibre gene expression is coordinated as a whole in different nuclei in the fibre is unclear. Here, the authors use single nucleus RNAseq and ATACseq to show the transcriptome heterogeneity of muscle nuclei in the adult mouse f
Externí odkaz:
https://doaj.org/article/8503a3a7129146fea7a01f6be4dfc5d6
Autor:
Matthieu Dos Santos, Stamatia Gioftsidi, Stéphanie Backer, Léo Machado, Frederic Relaix, Pascal Maire, Philippos Mourikis
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100694- (2021)
Summary: Single-nucleus RNA sequencing allows the profiling of gene expression in isolated nuclei. Here, we describe a step-by-step protocol optimized for adult mouse skeletal muscles. This protocol provides two main advantages compared to the widely
Externí odkaz:
https://doaj.org/article/012167ae4a2b4b66a5f210b57136fc20
Autor:
Séverine Marcos, Julie Moreau, Stéphanie Backer, Didier Job, Annie Andrieux, Evelyne Bloch-Gallego
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5405 (2009)
BACKGROUND: During development, neuronal growth cones integrate diffusible and contact guidance cues that are conveyed to both actin and microtubule (MT) cytoskeletons and ensure axon outgrowth and pathfinding. Although several post-translational mod
Externí odkaz:
https://doaj.org/article/5a0c453f09ff4fa48a80db2df97d8753