Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephanie Adams‐Tzivelekidis"'
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Inflammation induced by lung infection is a double-edged sword, moderating both anti-viral and immune pathogenesis effects; the mechanism of the latter is not fully understood. Previous studies suggest the vasculature is involved in tissue i
Externí odkaz:
https://doaj.org/article/298e4f96eba74047b28b7e392be57e41
Autor:
Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Justine Jou, Ian W. Folkert, Pengfei Yu, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The initiation and progression of cancer are intricately linked to the tumor microenvironment (TME). Understanding the function of specific cancer-TME interactions poses a major challenge due in part to the complexity of the in vivo microenv
Externí odkaz:
https://doaj.org/article/27a70ad4c8a74c5881020e751a7a5388
Autor:
Young-Jun Choi, Melissa S. Kim, Joshua H. Rhoades, Nicolette M. Johnson, Corbett T. Berry, Sarah Root, Qijun Chen, Yuhua Tian, Rafael J. Fernandez, III, Zvi Cramer, Stephanie Adams-Tzivelekidis, Ning Li, F. Brad Johnson, Christopher J. Lengner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 451-472 (2023)
Background & Aims: Dyskeratosis congenita (DC) is a telomere biology disorder caused primarily by mutations in the DKC1 gene. Patients with DC and related telomeropathies resulting from premature telomere dysfunction experience multiorgan failure. In
Externí odkaz:
https://doaj.org/article/097aee7b209740a1bf70038743eb0b74
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
bioRxiv
Inflammation upon infectious lung injury is a double-edged sword: while tissue-infiltrating immune cells and cytokines are necessary to control infection, these same factors often aggravate injury. Full appreciation of both the sources and targets of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f06f4517047ef22e053a3f66a0fc31b
https://europepmc.org/articles/PMC10245987/
https://europepmc.org/articles/PMC10245987/
Autor:
Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Ian W. Folkert, Pengfei Yu, Justine Jou, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner
SummaryThe initiation and progression of cancer are inextricably linked to the tumor microenvironment (TME). Understanding the function of specific cancer-TME interactions poses a major challenge due in part to the complexity of the in vivo microenvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ef31e3f6c1fd48e3f5c0fe8a6e7b68
https://doi.org/10.1101/2022.09.13.506996
https://doi.org/10.1101/2022.09.13.506996
Autor:
Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams‐Tzivelekidis, Yuhua Tian, Patrick A Williams, N Adrian Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton
Publikováno v:
EMBO reports. 23(11)
The intestinal epithelium exhibits a rapid and efficient regenerative response to injury. Emerging evidence supports a model where plasticity of differentiated cells, particularly those in the secretory lineages, contributes to epithelial regeneratio
Autor:
Yuhua Tian, Xin Wang, Zvi Cramer, Joshua Rhoades, Katrina N. Estep, Xianghui Ma, Stephanie Adams Tzivelekidis, Bryson W Katona, F Brad Johnson, Zhengquan Yu, Mario Andres Blanco, Christopher Lengner, Ning Li
Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally, with the majority of cases initiated by inactivation of the APC tumor suppressor. This results in the constitutive transcriptional activation of the canonical WNT signal tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::323fedb8ecb32d3a33efc381510be6f8
https://doi.org/10.1101/2022.07.26.501557
https://doi.org/10.1101/2022.07.26.501557
Autor:
Aaron I. Weiner, Gan Zhao, Hanna M. Zayas, Nicolas P. Holcomb, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E. Gentile, Dyuthi Reddy, Joey Wei, Gargi Palashikar, Kwaku K. Quansah, Andrew E. Vaughan
Publikováno v:
Cell reports. 41(11)
The lung exhibits a robust, multifaceted regenerative response to severe injuries such as influenza infection, during which quiescent lung-resident epithelial progenitors participate in two distinct reparative pathways: functionally beneficial regene
Autor:
Christopher J. Lengner, Corbett T. Berry, Joshua H. Rhoades, Stephanie Adams-Tzivelekidis, Zvi Cramer, F. Brad Johnson, Qijun Chen, Youngjun Choi, Nicolette M. Johnson, Melissa S. Kim, Sarah Root, Rafael Fernandez, Yuhua Tian, Ning Li
Patients with dyskeratosis congenita (DC) and related telomeropathies resulting from premature telomere dysfunction suffer from multi-organ failure. In the liver, DC patients present with nodular hyperplasia, steatosis, inflammation, and cirrhosis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabf41108c7a36495a0b9a59caa39c65
https://doi.org/10.1101/2021.11.19.469258
https://doi.org/10.1101/2021.11.19.469258
Autor:
Katherine M. Neupauer, Maria Fernanda de Mello Costa, Nilam S. Mangalmurti, Andrew E. Vaughan, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Gan Zhao, Gargi Palashikar
Publikováno v:
Science Advances
Repair of blood vessels after viral lung injury is achieved by resident endothelial cells and requires COUP-TF2.
Acute respiratory distress syndrome is associated with a robust inflammatory response that damages the vascular endothelium, impairi
Acute respiratory distress syndrome is associated with a robust inflammatory response that damages the vascular endothelium, impairi